Personalis Inc. (04X)
XBER 
Summary
Personalis, Inc. (PSNL) Q3 2025 Earnings Call Transcript
Personalis, Inc. ( PSNL ) Q3 2025 Earnings Call November 4, 2025 5:00 PM EST Company Participants Christopher Hall - President, CEO & Director Aaron Tachibana - CFO & COO Richard Chen - Executive VP of R&D and Chief Medical Officer Conference Call Participants Caroline Corner - Westwicke Partners, LLC Thomas Flaten - Lake Street Capital Markets, LLC, Research Division Mark Massaro - BTIG, LLC, Research Division Daniel Brennan - TD Cowen, Research Division Thomas VonDerVellen - Guggenheim Securities, LLC, Research Division Michael Matson - Needham & Company, LLC, Research Division John Wilkin - Craig-Hallum Capital Group LLC, Research Division Yu He - H.C. Wainwright & Co, LLC, Research Division Presentation Operator Good afternoon, and welcome to the Personalis Third Quarter 2025 Earnings Conference.
Personalis (PSNL) Reports Q3 Loss, Tops Revenue Estimates
Personalis (PSNL) came out with a quarterly loss of $0.24 per share versus the Zacks Consensus Estimate of a loss of $0.28. This compares to a loss of $0.64 per share a year ago.
Personalis (PSNL) Moves 20.5% Higher: Will This Strength Last?
Personalis (PSNL) saw its shares surge in the last session with trading volume being higher than average. The latest trend in earnings estimate revisions may not translate into further price increase in the near term.
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Personalis Inc. Profile
| Professional Services Industry | Industrials Sector | Christopher M. Hall CEO | XBER Exchange | US71535D1063 ISIN |
| US Country | 228 Employees | - Last Dividend | - Last Split | 20 Jun 2019 IPO Date |
Overview
Personalis, Inc. is a biotechnology firm, established in 2011 with its headquarters in Fremont, California, that specializes in the development and marketing of innovative cancer genomic tests and analytics. The company serves a broad international market, including regions such as the United States, Europe, and the Asia-Pacific. Personalis caters to the needs of pharmaceutical companies for translational research and biomarker discovery, aiding the development of personalized cancer therapies. Moreover, it provides sophisticated tests employed by physicians to identify cancer recurrence, monitor the evolution of the disease, and discover vital information for choosing appropriate therapy options. Its clientele encompasses pharmaceutical and biopharmaceutical companies, diagnostics companies, universities, non-profits, government entities, and individual patients.
Products and Services
- NeXT Personal
- ImmunoID NeXT
- NeXT Personal Dx
- NeXT Dx
- Whole Exome Sequencing (WES) and Whole Genome Sequencing (WGS)
This is a tumor-informed liquid biopsy test designed for the detection of minimal residual disease (MRD) and the recurrence of cancer. It enables personalized monitoring and treatment options by providing a deep insight into the molecular signature of an individual's cancer.
A tissue-based comprehensive test that combines whole exome (DNA) and whole transcriptome (RNA) sequencing data. Through advanced analytics, it offers a multi-dimensional view of the tumor and its microenvironment from a single sample, facilitating the development of targeted cancer therapies and immunotherapies.
Similar to NeXT Personal, this test offers tumor-informed liquid biopsy capabilities for the detection of MRD and cancer recurrence, specifically designed with a diagnostic focus to aid clinicians in the personalized treatment of cancer patients.
A comprehensive tumor profiling test that unlocks insights into the entire exome (DNA) and transcriptome (RNA) of a cancer patient. By providing matched tumor-normal analysis, it leverages detailed genomic information to better understand the disease and guide treatment options.
Personalis offers WES of cancer tissue and matched blood samples, and WGS on human samples for a variety of purposes including diagnostic tool development, research projects, and population sequencing initiatives. These services are complemented by the company’s sequencing and data analysis capabilities, supporting the broader research and medical community in uncovering new insights into cancer genomics.
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