The mean of analysts' price targets for PepGen (PEPG) points to a 75.4% upside in the stock. While this highly sought-after metric has not proven reasonably effective, strong agreement among analysts in raising earnings estimates does indicate an upside in the stock.
PepGen Inc. (PEPG) has seen its DM1 trials advance to phase 2 with a great reaction from markets. PEPG discontinued its DMD trials, which explains some of the reduced R&D expenses in the last 3 months and also some of the stock's declines earlier in the year. With only $45 million in net cash and marketable securities and maybe towards $1 billion in future R&D costs, potential equity raises with reflexivity risk are a consideration.
On Tuesday, PepGen Inc. PEPG announced its voluntary decision to temporarily pause the Phase 2 CONNECT2-EDO51 study of PGN-EDO51 in patients with Duchenne muscular dystrophy (DMD) until the company can review results from the 10 mg/kg cohort.
| Biotechnology Industry | Healthcare Sector | James G. McArthur CEO | NASDAQ (NGS) Exchange | 713317105 CUSIP |
| US Country | 79 Employees | - Last Dividend | - Last Split | 6 May 2022 IPO Date |
PepGen Inc. is a clinical-stage biotechnology company based in Boston, Massachusetts, that was established in 2018. The company's primary focus is on developing oligonucleotide therapeutics aimed at treating severe neuromuscular and neurologic diseases. With a dedicated approach to harnessing the potential of EDO peptides and oligonucleotide therapies, PepGen Inc. strives to bring innovative treatments forward for conditions that currently have limited therapeutic options.
Currently in Phase 2 clinical trial, PGN-EDO51 is PepGen Inc.'s leading product candidate. This EDO peptide is being developed to treat patients with Duchenne muscular dystrophy (DMD), a severe muscle wasting disorder. By advancing this treatment into clinical trials, the company aims to address the tremendous need for effective DMD therapies.
PepGen Inc. is also developing PGN-EDODM1, an EDO peptide-conjugated phosphorodiamidate morpholino oligomer (PMO) that has entered Phase 1 clinical trial for the treatment of myotonic dystrophy type 1. This condition, another serious neuromuscular disease, affects adults and children, leading to life-limiting muscle weakness. PGN-EDODM1 represents a pioneering step towards addressing this unmet medical need.
The company has a pipeline of EDO therapeutic candidates, including PGN-EDO53, PGN-EDO45, and PGN-EDO44, which are also aimed at treating Duchenne muscular dystrophy (DMD). These additional EDO peptides highlight PepGen Inc.'s commitment to developing a range of potential DMD treatments, offering hope for improved outcomes for patients afflicted by this debilitating condition.