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XSTU Exchange | Israel Country |
Can-Fite BioPharma Ltd. is an innovative clinical-stage biopharmaceutical company based in Ramat Gan, Israel, dedicated to the development of orally bioavailable small molecule therapeutic products. These products are aimed at treating a range of conditions including cancer, liver inflammatory diseases, and erectile dysfunction. Established in 1994 and originally named Can-Fite Technologies Ltd., the company underwent a name change to Can-Fite BioPharma Ltd. in January 2001, reflecting its specialized focus on biopharmaceuticals. With a strong commitment to addressing unmet medical needs, Can-Fite BioPharma has forged key collaborations, such as with CMS Medical for the development and commercialization of specific drug candidates and Univo Pharmaceuticals for the co-development of cannabis-based therapies for various diseases.
An advanced drug candidate targeted primarily at psoriasis, Piclidenoson has successfully completed Phase III clinical trials. Its oral administration and bioavailability make it a promising treatment option for patients. Furthermore, Can-Fite BioPharma explores its potential in addressing other autoimmune and inflammatory diseases, underpinning the company's versatile approach to drug development.
This promising compound is undergoing Phase III clinical trials for liver cancer treatment and Phase IIa for pancreatic cancer, illustrating its potential in combating some of the most challenging cancer types. Additionally, it is in a Phase IIb trial for metabolic associated steatohepatitis (MASH), showcasing the diverse applicability of Namodenoson in treating various severe conditions.
Still in the pre-clinical trial stage, CF602 is being developed to address erectile dysfunction. Representing Can-Fite BioPharma's venture into men's health, this compound demonstrates the company's commitment to expanding its therapeutic offerings beyond its traditional focus areas.
In addition to its pharmaceutical products, Can-Fite BioPharma is developing a commercial predictive biomarker blood test kit. This kit is designed to detect A3 adenosine receptor (A3AR) expressions, which are associated with various pathological conditions, thereby facilitating targeted therapy. It exemplifies the company's innovative approach in integrating diagnostics with therapeutics to enhance treatment efficacy.