Sagimet Biosciences Inc. (0O2)
XDUS 
Summary
0O2 Chart
Sagimet Biosciences Reports First Quarter 2025 Financial Results and Provides Corporate Updates
Phase 1 clinical trial to evaluate the pharmacokinetics (PK) of a combination of denifanstat and resmetirom expected to initiate in 2H 2025; data readout expected 1H 2026 Phase 1 clinical trial to evaluate the pharmacokinetics (PK) of a combination of denifanstat and resmetirom expected to initiate in 2H 2025; data readout expected 1H 2026
Sagimet Biosciences Reports Full Year 2024 Financial Results and Provides Corporate Updates
Denifanstat Phase 3 MASH program initiated in Q4 2024; patient screening expected to start in 1H 2025 Denifanstat received Breakthrough Therapy designation from FDA for MASH Clearance of Investigational New Drug (IND) application for FASN Inhibitor TVB-3567, to be developed for the treatment of acne SAN MATEO, Calif., March 12, 2025 (GLOBE NEWSWIRE) -- Sagimet Biosciences Inc. (Nasdaq: SGMT), clinical-stage biopharmaceutical company developing novel therapeutics targeting dysfunctional metabolic and fibrotic pathways, today reported financial results for the full year ended December 31, 2024, and provided recent corporate updates.
Sagimet Biosciences Announces Clearance of IND for FASN Inhibitor TVB-3567, to be Developed for the Treatment of Acne
TVB-3567 is the Company's second fatty acid synthase (FASN) inhibitor First-in-human Phase 1 trial initiation planned in 2025 SAN MATEO, Calif., March 11, 2025 (GLOBE NEWSWIRE) -- Sagimet Biosciences Inc. (Sagimet, Nasdaq: SGMT), a clinical-stage biopharmaceutical company developing novel therapeutics targeting dysfunctional metabolic and fibrotic pathways, today announced the clearance of its Investigational New Drug (IND) application for TVB-3567, the Company's second fatty acid synthase (FASN) inhibitor.
Sagimet Biosciences Inc. Dividends
Sagimet Biosciences Inc. Earnings
| 14 May 2025 Date | | - Cons. EPS | - EPS |
| 12 Mar 2025 Date | | - Cons. EPS | - EPS |
| 14 Nov 2024 Date | | - Cons. EPS | - EPS |
| 14 Aug 2024 Date | | - Cons. EPS | - EPS |
| 15 May 2024 Date | | - Cons. EPS | - EPS |
| 14 May 2025 Date | | - Cons. EPS | - EPS |
| 12 Mar 2025 Date | | - Cons. EPS | - EPS |
| 14 Nov 2024 Date | | - Cons. EPS | - EPS |
| 14 Aug 2024 Date | | - Cons. EPS | - EPS |
| 15 May 2024 Date | | - Cons. EPS | - EPS |
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Sagimet Biosciences Inc. Profile
| Biotechnology Industry | Healthcare Sector | Mr. David A. Happel CEO | XDUS Exchange | US7867001049 ISIN |
| US Country | 14 Employees | - Last Dividend | - Last Split | 14 Jul 2023 IPO Date |
Overview
Sagimet Biosciences Inc., originally founded as 3-V Biosciences, Inc., underwent a rebranding in August 2019 to better reflect its focused mission in the biomedical field. This clinical-stage biopharmaceutical company is at the forefront of developing innovative treatments targeting diseases caused by dysfunctional lipid metabolism pathways. With its incorporation in 2006, Sagimet Biosciences has dedicated its efforts to exploring the potential of fatty acid synthase (FASN) inhibitors. These compounds have shown promise in addressing a variety of conditions linked to lipid metabolism, underlying the company's commitment to advancing healthcare solutions from its headquarters in San Mateo, California. Its research and development pivot around Denifanstat and TVB-3567, reflecting a broader strategy to combat prevalent health issues like nonalcoholic steatohepatitis (NASH) and specific cancer types, along with other conditions such as acne that denote significant unmet medical needs.
Products and Services
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Denifanstat (Lead Drug Candidate)
As the flagship product of Sagimet Biosciences, Denifanstat signifies a breakthrough in the treatment of nonalcoholic steatohepatitis (NASH), a serious liver condition lacking effective FDA-approved treatments. This innovative therapy, derived from the company’s proprietary research into fatty acid synthase (FASN) inhibitors, showcases Sagimet’s commitment to addressing diseases with significant unmet needs. In addition to NASH, Denifanstat has the potential to offer a novel treatment solution for acne, further demonstrating the broad therapeutic applications of FASN inhibitors in managing conditions linked to lipid metabolism dysfunctions.
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TVB-3567 (FASN Inhibitor for Cancer)
TVB-3567 stands as Sagimet Biosciences’ pivotal entry into cancer therapy, embodying the company's innovative approach towards leveraging FASN inhibitors against various cancer types. This development aligns with the growing recognition of metabolic pathways, such as those governed by fatty acid synthase, as critical points of intervention in cancer treatment. Sagimet’s pursuit of TVB-3567 underscores a strategic focus on expanding the utility of its FASN inhibitor platform to tackle the complexities of cancer, aiming to provide patients with new, effective therapeutic options.
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