Syngene International Ltd. (SYNGENE)

Overview

Syngene International Limited stands as a prominent contract research and manufacturing organization, delivering comprehensive drug discovery and development services across a global landscape, including regions like India, Japan, Europe, the United States, among others. Incorporated in 1993 and based in Bengaluru, India, the company operates as a subsidiary of Biocon Limited. Through its extensive suite of services, Syngene caters to a diversified clientele encompassing pharmaceutical, biotechnology, nutrition, animal health, consumer goods, and specialty chemical industries. Additionally, it boasts strategic partnerships and collaborations with industry giants such as Bristol-Myers Squibb Co., Baxter Inc., and Amgen Inc., reinforcing its position in the pharmaceutical and biotechnological sectors.

Products and Services

The array of offerings by Syngene International Limited is broad and subdivided into distinct categories, designed to meet the versatile needs of its multi-industry clients. Each category comprises specialized services tailored for each stage of the drug development process, from initial discovery to commercial manufacturing.

• Discovery Chemistry Services: This encompasses synthetic and medicinal chemistry, library and peptide synthesis, biomolecular science, organic electronic materials, and computational and analytical chemistry. These services assist in the efficient discovery and preliminary developments of potential therapeutic compounds.
• Discovery Biology Services: Offers comprehensive support in recombinant DNA engineering, cell line development, hybridoma technology, sequencing, protein sciences, screening and assay biology, DMPK, in vivo pharmacology, toxicology, and biologicals. These are crucial for understanding the biological efficacy and safety profiles of new drugs.
• Chemical, Formulation, Analytical, and Clinical Development Services: Encompasses a wide range of services from the initial chemical synthesis of drug compounds to their formulation, analytical testing, and clinical development phases. This ensures the drug compounds are not only effective but also safe and stable.
• Commercial Manufacturing Services: Syngene provides large-scale manufacturing capabilities for drugs that have completed the development process and received regulatory approvals. This includes the production of Active Pharmaceutical Ingredients (APIs) and finished drug products.
• Lead Generation, Preclinical Development, API, and Drug Product Development Services: Syngene offers a comprehensive pipeline of services from lead generation through to the full-scale development of APIs and finished pharmaceutical products, ensuring seamless transition through the drug development stages.
• Clinical Trial Management and Related Services: The company provides an umbrella of clinical trial management services including pharmacokinetic analysis/bioanalytical, central lab, clinical data management, regulatory affairs, biostatistics, and medical writing. Such services are critical for the successful conduct of clinical trials and subsequent analysis of results.
• Specialty Modalities: Syngene extends its expertise to specialty modalities including peptides, oligonucleotides, antibody-drug conjugates, and targeted degradation/stabilization. This highlights its capabilities in addressing complex therapeutic needs and innovative drug formats.