β Company on track to begin ELEVATE-45-201 in Q3 2025 β β Follows recently received Medicines and Healthcare Products Regulatory Agency authorization in the United Kingdom for ELEVATE-45-201 β BOSTON, May 28, 2025 (GLOBE NEWSWIRE) -- Entrada Therapeutics, Inc. (Nasdaq: TRDA) today announced it has received authorization from the Health Authorities and Ethics Committees of multiple countries under the European Union Clinical Trial Regulation (EU-CTR) to initiate ELEVATE-45-201, a Phase 1/2 multiple ascending dose (MAD) clinical study of ENTR-601-45 in patients living with Duchenne muscular dystrophy (DMD) who are amenable to exon 45 skipping. βELEVATE-45-201 is the most advanced clinical study of a conjugated exon skipping therapy for individuals amenable to exon 45 skipping and offers the potential to address a large Duchenne subpopulation with significant unmet medical needs,β said Dipal Doshi, Chief Executive Officer at Entrada Therapeutics.
β Company on track to initiate ELEVATE-45-201 study in Q3 2025 β β ELEVATE-45 regulatory filings submitted in the EU, with regulatory review ongoing β β ELEVATE-45 is the second of three novel exon skipping Duchenne programs the Company expects to progress into global clinical development in 2025 β BOSTON, March 24, 2025 (GLOBE NEWSWIRE) -- Entrada Therapeutics, Inc. (Nasdaq: TRDA) today announced it has received authorization from the United Kingdom's Medicines and Healthcare Products Regulatory Agency (MHRA) and Research Ethics Committee to initiate ELEVATE-45-201. ELEVATE-45-201 is a Phase 1/2 multiple ascending dose (MAD) clinical study to evaluate Entrada's investigational medicinal product ENTR-601-45 for the potential treatment of Duchenne muscular dystrophy (DMD) in patients with a confirmed mutation in the DMD gene amenable to exon 45 skipping.
β Receives FDA authorization to initiate ELEVATE-44-102, a Phase 1b multiple ascending dose clinical study of ENTR-601-44 in adults living with Duchenne muscular dystrophy β β Follows recently received Medicines and Healthcare Products Regulatory Agency authorization in the United Kingdom for ELEVATE-44-201 β β Expands global ELEVATE-44 clinical program to include pediatric, adult, ambulatory and non-ambulatory patients with Duchenne muscular dystrophy β BOSTON, Feb. 24, 2025 (GLOBE NEWSWIRE) -- Entrada Therapeutics, Inc. (Nasdaq: TRDA) today announced that the United States Food and Drug Administration (FDA) has lifted the clinical hold on ENTR-601-44 and provided authorization to initiate ELEVATE-44-102, a Phase 1b multiple ascending dose (MAD) clinical study of ENTR-601-44 for the potential treatment of Duchenne muscular dystrophy (DMD) in adult patients with a confirmed mutation in the DMD gene amenable to exon 44 skipping. The global ELEVATE-44 program, which includes the ELEVATE-44-102 study in the U.S. and ELEVATE-44-201 outside of the U.S., will cover a broad population of patients with DMD and support evaluation of ENTR-601-44 in patients with both early and advanced disease.
![]() ENTR 20 Dec 2023 | Other | $0.01 Per Share |
![]() ENTR 21 Dec 2021 Paid | Other | $8.73 Per Share |
![]() ENTR 21 Dec 2020 Paid | Other | $1.65 Per Share |
![]() ENTR 19 Dec 2019 Paid | Other | $0.01 Per Share |
![]() ENTR 18 Dec 2018 Paid | Other | $0.03 Per Share |
![]() ENTR 20 Dec 2023 | Other | $0.01 Per Share |
![]() ENTR 21 Dec 2021 Paid | Other | $8.73 Per Share |
![]() ENTR 21 Dec 2020 Paid | Other | $1.65 Per Share |
![]() ENTR 19 Dec 2019 Paid | Other | $0.01 Per Share |
![]() ENTR 18 Dec 2018 Paid | Other | $0.03 Per Share |
ARCA Exchange | US Country |
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