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Omeros Corporation (OMER) Q3 2025 Earnings Call Transcript
Omeros Corporation ( OMER ) Q3 2025 Earnings Call November 13, 2025 4:30 PM EST Company Participants Gregory Demopulos - Co-Founder, Chairman, CEO & President David Borges - VP of Finance, Chief Accounting Officer & Treasurer Nadia Dac - VP & Chief Commercial Officer Conference Call Participants Jennifer Williams Brandon Folkes - H.C. Wainwright & Co, LLC, Research Division Stephen Brozak - WBB Securities, LLC, Research Division Olivia Brayer - Cantor Fitzgerald & Co., Research Division Presentation Operator Good afternoon, and welcome to today's earnings call for Omeros Corporation.
Omeros: Novo Nordisk's Licensing Deal Sends Shares Soaring, Makes Bull Case
Omeros Corporation's stock surged over 150% after licensing zaltenibart to Novo Nordisk for $340M upfront, plus milestones and royalties. The deal provides OMER with critical funding, alleviating bankruptcy concerns and supporting operations through 2027 as it pursues FDA approval for narsoplimab. Zaltenibart's unique MASP-3 inhibition offers advantages in PNH, attracting NVO, which seeks to diversify beyond semaglutide amid recent headwinds.
Omeros Corporation (OMER) Q2 2025 Earnings Call Transcript
Omeros Corporation (NASDAQ:OMER ) Q2 2025 Earnings Conference Call August 14, 2025 4:30 PM ET Company Participants Catherine A. Melfi - Chief Regulatory Officer & VP of Regulatory Affairs and Quality Systems David J.
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Omeros Corporation Profile
| Biotechnology Industry | Healthcare Sector | Gregory A. Demopulos CEO | XBER Exchange | US6821431029 ISIN |
| US Country | 202 Employees | - Last Dividend | - Last Split | 8 Oct 2009 IPO Date |
Overview
Omeros Corporation is a clinical-stage biopharmaceutical company engaged in the discovery, development, and commercialization of therapeutic products for a wide range of medical disorders. Founded in 1994 and based in Seattle, Washington, the company focuses on delivering innovative treatments for immunologic diseases, cancers, and conditions related to addiction and compulsive disorders. By targeting small-molecule and protein therapeutics, and specializing in orphan indications, Omeros is dedicated to addressing unmet medical needs, particularly in areas where treatment options are limited or non-existent.
Products and Services
- Narsoplimab (OMS721/MASP-2)
A pivotal clinical trial has been completed for Narsoplimab, a therapeutic candidate aimed at treating hematopoietic stem-cell transplant-associated thrombotic microangiopathy (TA-TMA). Additionally, it is undergoing a Phase III clinical trial for patients with immunoglobulin A nephropathy (IgAN) and a Phase II clinical trial to assess its efficacy in treating COVID-19.
- OMS1029
This long-acting, second-generation antibody is in Phase I clinical trials. It targets lectin pathway disorders, showcasing Omeros' commitment to addressing areas with significant unmet medical needs.
- OMS906
Currently, OMS906 has completed Phase II clinical trials. This product candidate is designed for the treatment of Paroxysmal nocturnal hemoglobinuria (PNH), complement 3 glomerulopathy (C3G), and other disorders associated with the alternative pathway of the complement system.
- OMS527
In Phase I clinical trials, OMS527 is being developed for the treatment of addictions and compulsive disorders, alongside movement disorders, demonstrating Omeros' foray into neurological conditions with significant impact on public health.
- Preclinical Development Programs
The company is also pursuing several ambitious preclinical development programs. These include MASP-2, targeting lectin pathway disorders; MASP-3 small-molecule inhibitors aimed at alternative pathway disorders; and a diverse array of immunotherapies such as Adoptive T-Cell and Chimeric Antigen Receptor (CAR) T-Cell Therapies and Immunomodulators/Immunotoxins/Cancer Vaccines for various cancers. These cutting-edge scientific endeavors highlight Omeros Corporation's dedication to pioneering treatments for complex conditions and diseases.
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