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Esperion Therapeutics, Inc. (ESPR) Presents at Jefferies London Healthcare Conference 2025 Transcript
Esperion Therapeutics, Inc. ( ESPR ) Jefferies London Healthcare Conference 2025 November 18, 2025 3:00 AM EST Company Participants Benjamin Halladay - Chief Financial Officer Conference Call Participants Yuchen Ding - Jefferies LLC, Research Division Presentation Yuchen Ding Jefferies LLC, Research Division Good morning. Welcome to the Jefferies London Healthcare Conference.
Esperion Therapeutics, Inc. (ESPR) Discusses Breaking the Statin Intolerance Barrier and Closing the Care Gap in Cardiovascular Health Transcript
Esperion Therapeutics, Inc. ( ESPR ) Discusses Breaking the Statin Intolerance Barrier and Closing the Care Gap in Cardiovascular Health November 11, 2025 2:00 PM EST Company Participants Sheldon Koenig - President, CEO & Director LeAnne Bloedon Conference Call Participants Dharmesh Patel Fatima Rodriguez Kyuwon Choi - Goldman Sachs Group, Inc., Research Division Joseph Pantginis - H.C. Wainwright & Co, LLC, Research Division Jason Zemansky - BofA Securities, Research Division Rick Miller - Cantor Fitzgerald & Co., Research Division Presentation Operator Good day, everyone.
ESPR's Q3 Earnings Lag Estimates, Revenues Rise Y/Y, Stock Down
Esperion's Q3 loss widens despite a 69% jump in revenues. Mixed results and investor jitters probably drag ESPR shares down 15%.
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Esperion Therapeutics Inc. Profile
| Specialty Retail Industry | Consumer Discretionary Sector | Sheldon L. Koenig CEO | LSE Exchange | US29664W1053 ISIN |
| US Country | 304 Employees | - Last Dividend | - Last Split | 26 Jun 2013 IPO Date |
Overview
Esperion Therapeutics, Inc. is a pioneering pharmaceutical company specialized in the development and commercialization of innovative medicines designed to combat elevated levels of low-density lipoprotein cholesterol (LDL-C). Established in 2008 and rooted in Ann Arbor, Michigan, Esperion has established itself as a key player in addressing hyperlipidemia, a major risk factor for cardiovascular diseases. Through strategic license and collaboration agreements with global pharmaceutical powerhouses such as Daiichi Sankyo Co. Ltd, Otsuka Pharmaceutical Co., Ltd, and Daiichi Sankyo Europe GmbH, Esperion enhances its capabilities to bring its novel treatment options to a broader patient population worldwide.
Products and Services
- NEXLETOL (bempedoic acid) and NEXLIZET (bempedoic acid and ezetimibe) tablets
- NILEMDO
- NUSTENDI
These oral, once-daily, non-statin medicines are developed by Esperion for the treatment of primary hyperlipidemia in adults. They are particularly targeted at patients with heterozygous familial hypercholesterolemia or atherosclerotic cardiovascular disease who need an additional reduction in LDL-C levels. By offering a non-statin alternative, these products provide a solution for patients who may not tolerate statin therapies well.
An innovative ATP Citrate Lyase (ACL) inhibitor, NILEMDO significantly lowers LDL-C and cardiovascular risk by impeding cholesterol biosynthesis and enhancing the up-regulation of LDL receptors. This product stands out for its direct action on cholesterol production pathways, offering a novel mechanism of action in the fight against hyperlipidemia.
A combination of bempedoic acid and ezetimibe, NUSTENDI is formulated to target elevated LDL-C. It offers a dual mechanism of action by not only inhibiting cholesterol biosynthesis (via bempedoic acid) but also reducing intestinal cholesterol absorption (via ezetimibe). This synergistic action makes NUSTENDI a potent option for patients requiring comprehensive LDL-C management.
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