Nuvation Bio Inc. (NUVB) Presents at Citi Annual Global Healthcare Conference 2025 Transcript
Nuvation Bio (NUVB) is downgraded from Buy to Hold as its stock price now reflects improved Ibtrozi rollout visibility and strong fundamentals. Ibtrozi's commercial launch is robust, with early patient uptake and revenue run-rate supporting a $300–$600 million forward revenue estimate for NUVB. Despite a solid balance sheet and pipeline potential, NUVB's current valuation no longer offers the deep discount that justified aggressive buying at lower prices.
Nuvation Bio Inc. ( NUVB ) Jefferies London Healthcare Conference 2025 November 19, 2025 10:00 AM EST Company Participants David Hung - Founder, President, CEO & Chairman Philippe Sauvage - CFO & Principal Financial Officer Conference Call Participants Farzin Haque - Jefferies LLC, Research Division Presentation Farzin Haque Jefferies LLC, Research Division Hi, everyone. My name is Farzin Haque.
| Biotechnology Industry | Healthcare Sector | David T. Hung CEO | NYSE Exchange | 67080N101 CUSIP |
| US Country | 273 Employees | - Last Dividend | - Last Split | 24 Aug 2020 IPO Date |
Nuvation Bio Inc. operates as a clinical-stage biopharmaceutical entity, dedicating its efforts toward the development of novel therapeutic candidates primarily in the field of oncology. Founded in 2018, the company is based in New York, New York, positioning itself as a pioneer in advancing cancer treatment options. Through its focus on cutting-edge research and development, Nuvation Bio Inc. aims to address the unmet medical needs in cancer care by leveraging its expertise in biopharmaceutical innovation to create a significant impact on patients' lives.
As the lead product candidate of Nuvation Bio Inc., NUV-868 is a BD2 selective oral small molecule BET inhibitor. This innovative therapy works through epigenetic regulation of proteins pivotal in tumor growth and differentiation, including key oncogenes like c-myc. By targeting BET proteins, NUV-868 aims to disrupt the cancer cell cycle, providing a novel avenue for cancer treatment.
NUV-1156 represents another cornerstone of Nuvation Bio's portfolio. It is an AR binder Xtandi designed to tackle advanced-stage prostate cancers. This product has the unique potential to be used in earlier lines of treatment that typically involve surgical prostatectomy, offering a less invasive option for patients. By focusing on advanced prostate cancer, NUV-1156 could fill a significant treatment gap in current cancer care practices.
The Drug-Drug Conjugate platform developed by Nuvation Bio brings a novel approach to the drug-conjugate class of anti-cancer therapies. This technology aims to deliver anti-cancer therapeutics directly to cancer cells, ensuring more targeted treatment modalities with potentially reduced side effects. The DDC platform exemplifies Nuvation Bio's commitment to innovation in drug delivery systems for oncology.
A part of the company's diverse oncology pipeline, NUV-1176 is a PARP inhibitor focused on addressing ER+ breast and ovarian cancer. By leveraging the mechanism of PARP inhibition, NUV-1176 seeks to exploit the innate vulnerabilities of cancer cells, thereby offering a potentially effective treatment option for patients suffering from these types of cancer.