Pieris Pharmaceuticals (NASDAQ: PIRS ) stock is rocketing higher on Wednesday after announcing a merger agreement with Palvella Therapeutics. Pieris Pharmaceuticals and Palvella Therapeutics will enact an all-stock transfer for this merger.
| Biotechnology Industry | Healthcare Sector | Stephen S. Yoder CEO | XFRA Exchange | US7207951036 ISIN |
| US Country | 46 Employees | - Last Dividend | 23 Apr 2024 Last Split | 13 Apr 2015 IPO Date |
Pieris Pharmaceuticals, Inc. is an innovative biotechnology firm established in 2001 with a head office located in Boston, Massachusetts. The company is engaged in the discovery and development of advanced biotechnological applications with a particular emphasis on immuno-oncology (IO). Through its strategic partnerships and cutting-edge research, Pieris Pharmaceuticals aims to catalyze advancements in the treatment of cancer and other serious diseases by harnessing the power of its proprietary 4-1BB bispecifics programs.
A groundbreaking bispecific Mabcalin compound co-developed with Les Laboratoires Servier and Institut de Recherches Internationales Servier, S095012 (PRS-344) uniquely targets PD-L1 and 4-1BB. This dual-targeting mechanism is designed to enhance the immune system's ability to fight cancer. Currently under phase 1 clinical studies, the compound promises to be a significant advancement in IO therapies.
In collaboration with Pfizer Inc., SGN-BB228 (PRS-346) is a novel CD228 x 4-1BB bispecific antibody-Anticalin compound. By targeting CD228 and 4-1BB, it leverages a unique pathway to stimulate an immune response against cancer cells. This product is part of Pieris Pharmaceuticals' effort to develop more effective cancer treatments and is also in phase 1 of clinical research.
A collaboration with Boston Pharmaceuticals has given rise to BOS-342 (PRS-342), a bispecific Mabcalin compound targeting GPC3 and 4-1BB. This innovative approach aims at exploiting the tumor antigen GPC3 for the therapeutic engagement of 4-1BB, a costimulatory receptor on T cells. The product is designed to bolster the immune system's ability to target and destroy cancer cells and is in the early stages of clinical testing.