Cullinan Therapeutics, Inc. (CGEM)
NASDAQ (NGS) NASDAQ (NGS) Primary Summary
Cullinan Therapeutics: Heading Toward Paydirt
Cullinan Therapeutics remains a compelling buy as zipalertinib approaches a key FDA decision for EGFR exon 20 insertion NSCLC. Zipalertinib demonstrates promising efficacy, including CNS activity and responses post-amivantamab, with pivotal phase 3 REZILIENT3 data expected later this year. CGEM's diversified pipeline in oncology and immunology, strong cash reserves, and operational runway into 2029 support continued optimism.
Cullinan Therapeutics, Inc. (CGEM) Discusses Promising Clinical Data for CLN-978 and Velinotamig in Autoimmune Diseases Transcript
Cullinan Therapeutics, Inc. (CGEM) Discusses Promising Clinical Data for CLN-978 and Velinotamig in Autoimmune Diseases Transcript
Cullinan Therapeutics: Cash-Rich With A Major 2027 FDA Catalyst
Cullinan Therapeutics's Zipalertinib NDA has been accepted, making its February 27, 2027, PDUFA date their clearest near-term catalyst. Zipalertinib targets EGFR exon 20 insertion NSCLC, a niche but still meaningful demographic that could expand over time with more trials for new indications. CGEM's CLN-978, Velinotamig, and CLN-049 add other interesting assets in their pipeline across autoimmune disease and AML.
Cullinan Therapeutics, Inc. Investors
| Name | Quantity | Cost | Value | Profit ($) | Gain (%) |
|---|---|---|---|---|---|
| CE Curtis Ellergodt Rothschild Investment LLC | 33 | $258.23 | $586.41 | $328.18 | 127.09% |
| BG Bart Gancher Intech Investment Management LLC | 14,913 | $112,980.37 | $263,661.84 | $150,681.47 | 133.37% |
 Point72 Asset Management LP Point72 Asset Management LP | 905,376 | $11.48M | $16.04M | $4.57M | 39.8% |
 Joseph Castro Nuveen LLC | 805,700 | $8.56M | $14.24M | $5.69M | 66.47% |
 Bobby Adusumilli SJS Investment Consulting Inc. | 43 | $533.83 | $764.11 | $230.28 | 43.14% |
Cullinan Therapeutics, Inc. Analysts
| Name | Quantity | Cost | Value | Profit ($) | Gain (%) |
|---|---|---|---|---|---|
 Robert Driscoll Wedbush | 597.79 | $7,998.45 | $10,562.99 | $2,564.54 | 32.06% |
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Cullinan Therapeutics, Inc. Profile
| Pharmaceuticals Industry | Healthcare Sector | Nadim Ahmed CEO | NASDAQ (NGS) Exchange | 230031106 CUSIP |
| US Country | 109 Employees | - Last Dividend | 31 Aug 2009 Last Split | - IPO Date |
Overview
Cullinan Therapeutics, Inc. is a leading biopharmaceutical company based in Cambridge, Massachusetts, dedicated to discovering and developing innovative oncology therapies aimed at improving the lives of cancer patients across the United States. Initially established in 2016 as Cullinan Oncology, Inc., the company underwent a name change to Cullinan Therapeutics, Inc. in April 2024, reflecting its broadened focus on a range of therapeutic solutions beyond oncology. Through its commitment to cutting-edge research and development, Cullinan Therapeutics has positioned itself at the forefront of the biopharmaceutical industry, leveraging strategic partnerships and advanced scientific methodologies to tackle some of the most challenging cancers.
Products and Services
- CLN-619: A monoclonal antibody currently undergoing Phase I clinical trial, CLN-619 is designed for the treatment of solid tumors. This lead program exemplifies Cullinan Therapeutics’ commitment to advancing cancer care through innovative therapeutic solutions.
- CLN-049: A humanized bispecific antibody in Phase I clinical trials, CLN-049 aims to treat acute myeloid leukemia or myelodysplastic syndrome. This product represents the company’s endeavor to address hematologic malignancies with targeted therapies.
- CLN-418: In Phase 1 clinical trial, CLN-418 is a human bispecific immune activator targeted at treating multiple solid tumors. Developed in collaboration with Harbour BioMed US Inc., this therapy showcases Cullinan Therapeutics' focus on harnessing the body’s immune response to combat cancer.
- Zipalertinib: A bioavailable small molecule for patients with non-small cell lung cancer, Zipalertinib is being developed under a co-development agreement with Taiho Pharmaceutical Co., Ltd. It highlights Cullinan Therapeutics’ efforts in targeting specific cancer mutations.
- CLN-617: A fusion protein in development for the treatment of solid tumors, CLN-617 demonstrates the company’s ongoing investment in alternative therapeutic modalities to expand its oncology portfolio.
- CLN-978: Targeting relapsed/refractory B-cell non-Hodgkin lymphoma, CLN-978 is a T cell engaging antibody. This development product further signifies Cullinan Therapeutics’ commitment to exploring novel approaches in cancer immunotherapy.
In addition, Cullinan Therapeutics has forged crucial strategic alliances, including a license and collaboration agreement with Adimab, LLC for antibody discovery and/or optimization. These partnerships enable the enhancement of its R&D capabilities and ensure the development of forward-thinking cancer therapies.
