CenterPoint Energy Inc. (0HVF)
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TransCon® hGH Boosted Treatment Benefits of TransCon® CNP in Children with Achondroplasia at Week 26 Interim Analysis of the Phase 2 COACH Trial
- For the TransCon CNP treatment-naïve cohort, combination treatment resulted in mean annualized growth velocity (AGV) of 9.14 cm/year, with an improvement in mean ACH height Z-score of +0.53 over 26 weeks - For the TransCon CNP-treated cohort, combination treatment resulted in mean AGV of 8.25 cm/year, with an improvement in mean ACH height Z-score of +0.44 over 26 weeks - The combination of TransCon hGH and TransCon CNP demonstrated accelerated improvement in body proportionality at Week 26, aligning with the increase in linear growth - Safety and tolerability data consistent with those observed for TransCon hGH and TransCon CNP monotherapies; combination treatment was generally well tolerated, with generally mild treatment-emergent adverse events (TEAEs) - Ascendis to host conference call today at 8:00 am ET COPENHAGEN, Denmark, June 09, 2025 (GLOBE NEWSWIRE) -- Ascendis Pharma A/S (Nasdaq: ASND) today announced Week 26 interim analysis results from its ongoing COACH Trial, the first clinical trial to evaluate combination treatment with once-weekly investigational TransCon CNP (navepegritide) and once-weekly TransCon hGH (lonapegsomatropin) in children with achondroplasia. Results demonstrated that TransCon hGH boosted treatment benefits of TransCon CNP, resulting in significant growth and proportionality improvements in children with achondroplasia after 26 weeks of combination treatment, with a safety and tolerability profile consistent with those observed for TransCon hGH and TransCon CNP monotherapies.
2025 Atlantic Hurricane Season: CenterPoint Energy emphasizes preparedness with critical resiliency efforts completed before June 1; urges customers to have an emergency plan and practice that plan
Historic series of Greater Houston Resiliency Initiative key improvements completed ahead of schedule to strengthen the grid and reduce the impact of outages from major storms Joint emergency response exercise completed; community safety and preparedness events continue with emergency officials and local partners CenterPoint continues proactive outreach and communication efforts across Greater Houston service area to help customers prepare for upcoming storm season HOUSTON , June 3, 2025 /PRNewswire/ -- With the 2025 Atlantic hurricane season officially underway, CenterPoint Energy is reinforcing the resiliency and preparedness efforts the company already completed to strengthen grid resiliency, improve local emergency coordination and help communities and customers better prepare for potential severe weather. Last month, CenterPoint held its 2025 emergency response exercise as part of a coordinated effort with public officials, emergency response managers and community partners to improve local cooperation and response efforts.
FDA Accepts TransCon® CNP NDA for Priority Review
– Once-weekly TransCon CNP demonstrated significantly higher annualized growth velocity, the primary endpoint, compared to placebo
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CenterPoint Energy Inc. Profile
| General Utilities Industry | Utilities Sector | Mr. Jason P. Wells CPA CEO | LSE Exchange | US15189T1079 ISIN |
| US Country | 8,872 Employees | 15 May 2025 Last Dividend | 1 Oct 2002 Last Split | 2 Jan 1970 IPO Date |
Overview
CenterPoint Energy, Inc. is a notable public utility holding company based in the United States, with its origins tracing back to 1866. The company's headquarters are situated in Houston, Texas, reflecting its strong presence in several states, including Indiana, Louisiana, Minnesota, Mississippi, Ohio, and Texas. It operates through two primary segments: Electric and Natural Gas. CenterPoint Energy plays a critical role in providing transmission, distribution, and generation services for electricity, while also delivering natural gas to a wide array of customers, ranging from residential to industrial and institutional sectors. The company’s infrastructure and operations are substantial, with a notable number of metered customers and extensive facilities that underline its capacity and commitment to energy distribution and services.
Products and Services
- Electric Transmission and Distribution
- Natural Gas Sales and Distribution
- Pipeline Connections and Repair Services
This segment focuses on the delivery of electricity to customers, alongside managing electric generation assets. CenterPoint Energy also partakes in optimizing these assets within the wholesale power market, ensuring reliable electricity supply and distribution across its service territories.
CenterPoint Energy is engaged in the sales and distribution of natural gas to diverse customer sectors including residential, commercial, industrial, and institutional clients. The company's operations in this segment highlight its role in ensuring the consistent provision of natural gas, facilitated through a comprehensive network of pipelines and service connections.
Through its Natural Gas segment, CenterPoint Energy maintains permanent pipeline connections by interfacing with various interstate and intrastate pipeline companies. Additionally, it offers maintenance and repair services for home appliances, predominantly in Minnesota. This service extends to providing home repair protection plans through third parties in select states, adding an essential layer of customer support and service reliability.
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