BridgeBio Pharma, Inc. (2CL)
Summary
2CL Chart
BridgeBio: "Strong Buy" Attruby Differentiation And Several NDA Submissions In Play
BridgeBio Pharma (BBIO) remains a "Strong Buy," driven by regulatory approvals, robust pipeline progress, and significant commercial momentum for Attruby in ATTR-CM. Company has achieved U.S. and international approvals for acoramidis, with Q1 2026 U.S. net product revenue reaching $180.6 million, and is pursuing further pipeline expansion. Positive phase 3 PROPEL 3 data for oral infigratinib in achondroplasia supports an NDA submission in Q3 2026, targeting a $2.9B global market.
How a Rival's Clinical Setback Sent BBIO Stock to a 52-Week High
BridgeBio Pharma hit a 52-week high after a rival's phase III setback boosts confidence in Attruby's competitive position in ATTR-CM.
BridgeBio Pharma (BBIO) Moves 15.1% Higher: Will This Strength Last?
BridgeBio Pharma (BBIO) witnessed a jump in share price last session on above-average trading volume. The latest trend in earnings estimate revisions for the stock doesn't suggest further strength down the road.
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BridgeBio Pharma, Inc. Profile
| Biotechnology Industry | Healthcare Sector | Neil Kumar CEO | XETRA Exchange | US10806X1028 ISIN |
| US Country | 725 Employees | - Last Dividend | - Last Split | 27 Jun 2019 IPO Date |
Overview
BridgeBio Pharma, Inc. stands as a prominent figure in the commercial-stage biopharmaceutical sector, dedicated to developing groundbreaking medicines aimed at treating genetic diseases and cancers. Since its inception in 2015, the company has been at the forefront of medical research, leveraging advanced scientific methods to discover, create, test, and deliver transformative treatments. Operating out of Palo Alto, California, BridgeBio Pharma is fuelled by collaborations and license agreements with esteemed institutions such as the Leland Stanford Junior University and Leidos Biomedical Research, Inc. Through its relentless pursuit of medical innovation, BridgeBio Pharma strives to offer new hope to patients facing some of the most challenging medical conditions.
Products and Services
- AG10
This compound is a next-generation oral small molecule designed to be a near-complete TTR stabilizer. Currently in Phase 3 clinical trials, AG10 targets the treatment of TTR amyloidosis or transthyretin amyloid cardiomyopathy (ATTR-CM), a significant advancement in addressing this condition.
- Low-dose Infigratinib
An oral FGFR1-3 selective tyrosine kinase inhibitor, low-dose infigratinib is under a Phase 3 double-blinded, placebo-controlled pivotal study. It represents a potential treatment option for children with achondroplasia, showcasing BridgeBio Pharma’s commitment to addressing rare genetic growth disorders.
- BBP-631
BridgeBio Pharma is advancing BBP-631, an AAV5 gene transfer product candidate, through a Phase 1/2 clinical trial. This innovative therapy targets congenital adrenal hyperplasia (CAH) caused by 21-hydroxylase deficiency (21OHD), offering a novel gene therapy approach to this adrenal disorder.
- Encaleret
A small molecule antagonist of the calcium sensing receptor (CaSR), Encaleret is currently in a phase 3 clinical trial. This product aims to treat autosomal dominant hypocalcemia type 1 (ADH1), underscoring the company's focus on developing treatments for rare metabolic disorders.
- BBP-418
In Phase 3 clinical trial, BBP-418 is a glycosylation substrate pro-drug for the treatment of limb-girdle muscular dystrophy type 2I/R9 (LGMD2I/R9). This highlights BridgeBio Pharma’s commitment to combating muscular dystrophies through cutting-edge therapies.
