Shanghai Model Organisms Center Inc. (688265)

Overview

Founded in 2000 and based in Shanghai, China, Shanghai Model Organisms Center, Inc. specializes in the research, development, production, sale, and provision of technical services related to genetically modified animal models. Utilizing groundbreaking gene editing technologies, the company focuses on the creation and manipulation of model organisms including mice, rats, zebrafish, and nematodes. These organisms serve as carriers for introducing or deleting specific DNA fragments, facilitating advanced research in various genetic and biomedical fields. The company’s contributions are pivotal in the study and treatment of numerous diseases, offering substantial resources for scientific and medical communities worldwide.

Products and Services

The company’s portfolio encompasses a broad spectrum of products and services tailored to fulfill the demands of genetics research, pharmaceutical development, and preclinical testing. These include:

• Toolbox of Mice: Features disease-specific mice models for studying rare, infectious, and nervous system diseases, alongside models with spontaneous tumors. These resources aid in understanding disease mechanisms and testing potential treatments.
• Target Humanized Knockins: Provides models with tumor targets, immune checkpoints, complements, cytokines, and metabolic and other targets. These knockin models are crucial for researching human diseases and developing targeted therapies.
• Rat Models: Offers a range of rat models including humanized drug targets, immunodeficient models, specific disease models, reporter models, and Cre-driver models. Like mice, these rat models play an essential role in drug development and genetic analysis.
• Cell Models: Includes a variety of cell models such as reporter labeled, primary, wild-type, and others for in-vitro studies and drug testing, providing a complementary approach to live animal models.
• Colony Management: Offers comprehensive services including cryopreservation, cryorecovery, housing, management, genotyping analysis, and breeding services to support researchers in maintaining genetic strains and conducting experiments.
• Auxiliary Apparatuses: Supplies essential equipment such as the e-BLOT WB imaging system, enhancing the efficiency and accuracy of research processes.
• Model Customization: Provides bespoke model creation utilizing advanced gene editing technologies such as ES cell targeting, CRISPR, and transgene techniques, enabling precise genetic modifications for specific research needs.
• Preclinical Services: Offers a suite of preclinical services including non-GLP toxicology, pharmacokinetics, phenotype analysis, and pharmacodynamics, crucial for advancing drug development and understanding the pharmacological properties of potential treatments.

Through these comprehensive offerings, Shanghai Model Organisms Center, Inc. supports breakthroughs in the understanding and treatment of critical therapeutic areas such as oncology; and nervous, autoimmune, and digestive system diseases.