Connect Biopharma Holdings Ltd. (CNTB)
NASDAQ (NMS) NASDAQ (NMS) Primary Summary
CNTB Chart
Connect Biopharma COPD Study Shows 81% Cut in Treatment Failures
Connect Biopharma NASDAQ: CNTB reported top-line results from its Seabreeze STAT Phase II study of rademikibart in patients experiencing acute exacerbations of chronic obstructive pulmonary disease, or COPD. The company said the study met its primary objective, showing reductions in treatment failures during the month after an exacerbation.
Connect Biopharma Holdings Limited (CNTB) Discusses Topline Results of Seabreeze STAT Study Evaluating Rademikibart for COPD Exacerbations Transcript
Connect Biopharma Holdings Limited (CNTB) Discusses Topline Results of Seabreeze STAT Study Evaluating Rademikibart for COPD Exacerbations Transcript
Connect Biopharma Holdings Limited (CNTB) Discusses Topline Results of Rademikibart Phase 2 Study for Acute Asthma Exacerbations Transcript
Connect Biopharma Holdings Limited (CNTB) Discusses Topline Results of Rademikibart Phase 2 Study for Acute Asthma Exacerbations Transcript
Connect Biopharma Holdings Ltd. Investors
| Name | Quantity | Cost | Value | Profit ($) | Gain (%) |
|---|---|---|---|---|---|
| CD Charlie Durham Sterling Capital Management LLC | 150 | $309 | $135.93 | -$173.07 | -56.01% |
 Joseph Castro Nuveen LLC | 19,773 | $40,732.38 | $17,918.29 | -$22,814.09 | -56.01% |
 Regan O'Neill Burkehill Global Management LP | 150,000 | $393,000 | $135,900 | -$257,100 | -65.42% |
 Hui Fai Tam Caitong International Asset Management Co. Ltd. | 66 | $135.96 | $59.81 | -$76.15 | -56.01% |
 Michael Souza Koa Wealth Management, LLC | 49,600 | $74,896 | $44,015.04 | -$30,880.96 | -41.23% |
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Connect Biopharma Holdings Ltd. Profile
| Biotechnology Industry | Healthcare Sector | Barry D. Quart CEO | NASDAQ (NMS) Exchange | G23549101 CUSIP |
| US Country | 64 Employees | - Last Dividend | - Last Split | - IPO Date |
Overview
Connect Biopharma Holdings Limited is a clinical-stage biopharmaceutical company dedicated to the discovery and development of novel therapies aimed at treating T cell-driven inflammatory diseases. Founded in 2012 and headquartered in San Diego, California, the company focuses on leveraging its expertise in functional T cell assays to screen and identify potent product candidates. These candidates target validated immune mediators with the goal of addressing significant unmet medical needs in inflammatory disorders. Connect Biopharma's strategic approach combines the development of both small molecules and antibodies to create a diverse pipeline capable of confronting various facets of immune system dysregulation.
Products and Services
- Rademikibart (formerly CBP-201)
- Icanbelimod (formerly CBP-307)
This leading product candidate is an antibody that specifically targets interleukin-4 receptor alpha, a critical mediator in the pathogenesis of several inflammatory diseases. Designed with the intention of disabling this pathway, rademikibart has moved into Phase 3 studies, exploring its effectiveness and safety in conditions such as atopic dermatitis and asthma. The targeting of interleukin-4 receptor alpha represents a rational and scientifically backed strategy to dampen the inflammatory response characteristic of these disorders, positioning rademikibart as a potentially pivotal therapy in the landscape of immunologically driven diseases.
This oral small molecule drug functions as a modulator of Sphingosine 1-Phosphate Receptor 1, a crucial component in the immune system's ability to mediate inflammatory responses. Currently under Phase 2 clinical development, icanbelimod is being tested for its efficacy and safety in the management of ulcerative colitis and Crohn's disease, two debilitating inflammatory bowel diseases. The molecule's mechanism of action offers a targeted approach to modulating disease activity, aiming to balance immune response without compromising overall immune competence, thereby offering hope for patients with these chronic conditions.
Contact Information
