Generate Biomedicines, Inc. (GENB)
NASDAQ (NMS) NASDAQ (NMS) Primary Summary
GENB Chart
Generate Biomedicines: The Dosing Interval Is The Moat, Not The Algorithm
Generate Biomedicines offers a compelling long-acting asthma biologic, golukibart (GB-0895), targeting twice-yearly dosing and broad phenotype efficacy. GENB leads the TSLP antagonist race with two global Phase 3 trials underway, aiming to displace Tezspire and capitalize on significant asthma and COPD market upside. Cash runway extends into early 2028, but Phase 3 trial costs and potential dilution before topline data are key risks to monitor.
Generate Biomedicines stock jumps as post-IPO lock-up set to expire
Shares of Generate Biomedicines Inc (NASDAQ:GENB) jumped more than 20% on Tuesday as investors positioned ahead of the expiration of the company's post-IPO lock-up period. The lock-up, which ends Wednesday, will free company insiders, early investors and major shareholders to sell shares issued as part of Generate's $400 million initial public offering earlier this year, which included 25 million shares.
Generate Biomedicines, Inc. Investors
| Name | Quantity | Cost | Value | Profit ($) | Gain (%) |
|---|---|---|---|---|---|
 John H. Burbank III Passport Capital LLC | 1.42M | $17.8M | $17.97M | $170,832.24 | 0.96% |
| CD Charlie Durham Sterling Capital Management LLC | 212 | $3,576 | $2,654.24 | -$921.76 | -25.78% |
| NM Nir Messafi Deep Track Capita LLP | 1.33M | $22.55M | $17.11M | -$5.44M | -24.13% |
 Joseph Castro Nuveen LLC | 44,470 | $750,209 | $556,764.4 | -$193,444.6 | -25.79% |
| MPM Mark P. Mennitt CenterBook Partners LP | 131,560 | $1.64M | $1.56M | -$82,882.8 | -5.04% |
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Generate Biomedicines, Inc. Profile
| Capital Markets Industry | Financials Sector | Michael T. Nally CEO | NASDAQ (NMS) Exchange | 370920100 CUSIP |
| US Country | 312 Employees | - Last Dividend | - Last Split | - IPO Date |
Overview
Generate Biomedicines, Inc. is a pioneering company specializing in generative biology within the pharmaceutical sector, leveraging machine learning techniques for drug discovery and development. The company focuses on the programming of innovative protein therapeutics, employing protein-based modalities to advance drug development processes. With its headquarters located in Somerville, Massachusetts, Generate Biomedicines was established in 2018 and underwent a name change from Generate Biologics, Inc. to Generate Biomedicines, Inc. in February 2020. The company’s mission is to tackle therapeutic challenges that traditional technologies often cannot address, utilizing an integrative approach combining computational innovation with scalable biohardware.
Products and Services
- GB-0895: An investigational long-acting anti-TSLP monoclonal antibody currently in development specifically aimed at severe asthma treatment. This product is designed for administration every six months, offering a novel approach to managing this chronic respiratory condition.
- GB-4362: A monoclonal antibody acting as an MMAE payload neutralizer, which is developed to enhance the therapeutic effectiveness of cancer treatments by mitigating side effects and improving targeted delivery.
- GB-5267: A MUC16 CAR-T Cell therapy designed to target and eliminate tumor cells expressing the MUC16 antigen. This innovative treatment aims to enhance the body's immune response against cancer and provides a personalized therapeutic option for patients.
- Generate Platform: A cutting-edge platform that is therapeutic area and protein modality agnostic, designed to integrate computational advancements with scalable biohardware. This platform is aimed at addressing complex therapeutic challenges that exceed the capabilities of conventional technologies.
Contact Information
