hVIVO plc (HVO)

Overview

hVIVO plc, previously known as Open Orphan Plc until its rebranding in October 2022, stands as a prominent entity in the pharmaceutical service and contract research domain. Headquartered in London, the United Kingdom, the company specializes in executing human challenge clinical trials which are pivotal for the testing of vaccines and antivirals. Serving an array of clients including big pharma, biotech organizations, government bodies, and public health institutions, hVIVO plays a crucial role in advancing the development and understanding of various medical interventions against infectious diseases.

Products and Services

• Human Challenge Study Models - hVIVO has developed an extensive portfolio of human challenge study models for a variety of conditions. These include Respiratory Syncytial Virus (RSV), influenza, human rhinovirus, asthma, malaria, cough, and Chronic Obstructive Pulmonary Disease (COPD), among others. The company is also in the process of developing a COVID-19 human challenge study model. These models are critical for understanding disease mechanisms, assessing vaccine efficacy, and evaluating antiviral drugs in a controlled environment.
• Specialized Virology and Immunology Laboratory Services - The company's state-of-the-art virology and immunology laboratories offer a comprehensive suite of services to support both pre-clinical and clinical stages of respiratory drug and vaccine discovery and development. These services are designed to provide valuable insights into the efficacy and safety of pharmaceutical interventions.
• Pre-Clinical and Early Clinical Research Services - hVIVO provides a range of research services aimed at the early stages of drug and vaccine development. This includes observational and interventional study designs, aiding in the transition from pre-clinical theories to clinical trials.
• Sales and Marketing Services - To facilitate the commercialization of pharmaceutical products, hVIVO offers bespoke sales and marketing services. These are tailored to enhance the market presence and reach of new drugs and vaccines.
• Data Management and Statistics Services - Crucial for the successful analysis and interpretation of clinical trial data, hVIVO's data management and statistics services ensure the integrity and reliability of research findings, aiding in regulatory submissions and publications.
• Drug Development Consultancy and Services - hVIVO's consultancy services cater to the strategic needs of drug development, offering expertise in regulatory affairs, clinical trial design, and market access strategies. This comprehensive support streamlines the path to drug approval and commercial success.