NanoViricides (NYSE-A:NNVC), the US clinical-stage drugmaker, has said its lead drug candidate NV-387 could be effective against the Bundibugyo strain of Ebola virus that has prompted the World Health Organisation to declare a global health emergency. The WHO designated the outbreak in eastern Democratic Republic of Congo a Public Health Emergency of International Concern on 17 May, after the virus killed at least 88 people across 336 suspected cases, with two infections also confirmed in neighbouring Uganda.
NanoViricides (NYSE-A:NNVC) said it has entered into a securities purchase agreement with a single institutional investor for gross proceeds of approximately $2 million in a registered direct offering. Under the terms of the agreement, the company will sell just over 1.3 million common shares, or pre-funded warrants in lieu thereof, together with accompanying warrants to purchase an equal number of common shares.
NanoViricides (NYSE-A:NNVC) is pointing to its lead drug candidate NV-387 as a potential solution to a critical gap in infectious disease preparedness, as a deadly hantavirus outbreak aboard a cruise ship triggers a costly global containment effort. The Connecticut-based clinical-stage company said NV-387 has completed Phase I clinical trials for safety and tolerability in healthy volunteers and has shown effectiveness against multiple virus families in lethal animal models, including coronaviruses, RSV, influenza, monkeypox and measles, tested via the same respiratory route through which Andes hantavirus spreads.
| Biotechnology Industry | Healthcare Sector | Anil R. Diwan CEO | XMUN Exchange | US6300873022 ISIN |
| US Country | 7 Employees | - Last Dividend | 24 Sep 2019 Last Split | 26 Oct 2005 IPO Date |
NanoViricides, Inc. is a pioneering clinical stage nano-biopharmaceutical company focused on the discovery, development, and commercialization of novel drugs for the treatment of viral infections. Founded in 2005 and based in Shelton, Connecticut, the company leverages its proprietary nanoviricide® technology to craft innovative therapies aimed at various viral diseases. This technology employs biomimetic strategies to create drugs that mimic natural virus-binding mechanisms, allowing for targeted delivery of antiviral payloads directly into infected cells while sparing healthy ones. Through its advanced research and clinical trials, NanoViricides aims to bring new solutions to market that address unmet medical needs in the management of viral infections.
The following are the key products and services developed by NanoViricides, Inc.:
This drug is currently undergoing phase 1a/1b clinical trials for the treatment of COVID-19. It represents the company's commitment to addressing the global pandemic by harnessing their nanoviricide technology to target and neutralize the virus.
Designed specifically for pediatric cases, these semi-solid fixed-dose forms are in phase 1a/1b human clinical trials. They allow for body-weight-based dose titration, offering a potentially safer and more effective treatment option for children suffering from COVID-19.
This versatile formulation is aimed at treating severe cases of COVID-19 that have not yet required hospitalization. It can be administered as an injection or delivered directly into the lungs using a nebulizer. This method seeks to directly target the primary site of infection by many respiratory viruses, potentially offering a significant advantage in treating diseases that can lead to severe pneumonia.
The cornerstone of NanoViricides' offerings, this platform technology is designed to carefully mimic the envelope of virus particles. It facilitates the delivery of antiviral drugs directly into infected cells, disrupting the virus's replication cycle with minimal toxicity to healthy cells. This technology represents a broad-spectrum approach capable of targeting a variety of enveloped viral infections beyond COVID-19, including influenza, RSV, and more.