Prelude Therapeutics (PRLD) might move higher on growing optimism about its earnings prospects, which is reflected by its upgrade to a Zacks Rank #2 (Buy).
Prelude Therapeutics Incorporated (PRLD) Presents at Goldman Sachs 47th Annual Global Healthcare Conference 2026 Transcript
The average of price targets set by Wall Street analysts indicates a potential upside of 33.6% in Prelude Therapeutics (PRLD). While the effectiveness of this highly sought-after metric is questionable, the positive trend in earnings estimate revisions might translate into an upside in the stock.
| Name | Quantity | Cost | Value | Profit ($) | Gain (%) |
|---|---|---|---|---|---|
John H. Burbank III Passport Capital LLC | 10.12M | $305.1M | $44.24M | -$260.86M | -85.5% |
Point72 Asset Management LP Point72 Asset Management LP | 16,329 | $47,354.04 | $71,398.55 | $24,044.51 | 50.78% |
| DP Drew Phillips Fortitude Family Office LLC | 230 | $787 | $986.58 | $199.58 | 25.36% |
| Biotechnology Industry | Healthcare Sector | Krishna Vaddi CEO | NASDAQ (NGS) Exchange | 74065P101 CUSIP |
| US Country | 79 Employees | - Last Dividend | - Last Split | 25 Sep 2020 IPO Date |
Prelude Therapeutics Incorporated is a clinical-stage biopharmaceutical company engaged in the quest to discover and develop novel precision cancer medicines aimed at addressing the needs of underserved patients. With a strategic focus on developing innovative therapeutic agents for various forms of cancer, the company pursues research and development with a patient-centric approach. Prelude Therapeutics, established in 2016 and headquartered in Wilmington, Delaware, positions itself at the forefront of cancer treatment by targeting specific malignant conditions through a detailed understanding of cancer biology and patient genetics.
Designed as a myeloid cell leukemia-1 (MCL-1) inhibitor, PRT1419 is currently in Phase 1 clinical trials. This investigational drug targets selected relapsed/refractory myeloid or B-cell malignancies, aiming to offer a new therapeutic approach for patients with these challenging forms of cancer.
A cyclin-dependent kinase (CDK) in development, PRT2527, is undergoing Phase 1 clinical trials to evaluate its efficacy in treating advanced solid tumors. Through inhibiting specific CDKs, PRT2527 seeks to impair the proliferation of cancer cells, offering a potential pathway for treating various solid malignancies.
PRT3645 is a cyclin-dependent kinase 4/6 (CDK4/6) inhibitor being assessed in Phase 1 clinical trials for its utility in the treatment of advanced and metastatic solid tumors. By targeting CDK4/6, PRT3645 aims to hinder cancer cell growth and proliferation, representing a novel approach to tackling aggressive and advanced forms of cancer.
Entering Phase 2/3 clinical trials, PRT3879 is a SMARCA2 selective protein degrader being explored for the treatment of advanced and metastatic solid tumors that demonstrate loss of SMARCA4 due to truncating mutation and/or deletion. This innovative therapy focuses on a specific genetic aberration, offering hope for patients with tumors that are difficult to treat with traditional therapies.
The company's CDK9 program revolves around the regulator of cancer-promoting transcriptional programs, including MCL1, MYC, and MYB. By targeting CDK9, Prelude aims to disrupt these critical pathways, thereby inhibiting cancer cell growth and survival. This research-focus underscores the company's commitment to unravelling complex cancer biology for the development of more effective treatments.