Vertex Pharmaceuticals Incorporated (VRTX)
Summary
VRTX Chart
Here is What to Know Beyond Why Vertex Pharmaceuticals Incorporated (VRTX) is a Trending Stock
Vertex (VRTX) has been one of the stocks most watched by Zacks.com users lately. So, it is worth exploring what lies ahead for the stock.
VRTX's Q4 Earnings Miss Mark, Revenues Beat on Higher Product Sales
Vertex Q4 earnings miss estimates, but revenues top forecasts on strong CF sales and momentum from new launches like Alyftrek, Casgevy and Journavx.
Vertex (VRTX) Q4 Earnings: How Key Metrics Compare to Wall Street Estimates
Although the revenue and EPS for Vertex (VRTX) give a sense of how its business performed in the quarter ended December 2025, it might be worth considering how some key metrics compare with Wall Street estimates and the year-ago numbers.
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Vertex Pharmaceuticals Incorporated Profile
| Biotechnology Industry | Healthcare Sector | Reshma Kewalramani CEO | XWBO Exchange | US92532F1003 ISIN |
| US Country | 6,100 Employees | - Last Dividend | 24 Aug 2000 Last Split | 24 Jul 1991 IPO Date |
Overview
Vertex Pharmaceuticals Incorporated stands at the forefront of biotechnology innovation, focusing its efforts on the development and commercialization of therapies aimed at treating cystic fibrosis (CF), a debilitating genetic disorder. Since its establishment in 1989, the company has been pioneering in its approach to providing groundbreaking treatments that significantly improve the lives of those affected by CF. Operating from its headquarters in Boston, Massachusetts, Vertex extends its impact globally through the marketing of its advanced therapeutic solutions. Beyond cystic fibrosis, the company's research pipeline explores treatments for a variety of serious conditions including pain management, sickle cell disease, beta thalassemia, focal segmental glomerulosclerosis, Type 1 Diabetes, and cancer. Vertex's commitment to innovation is further underscored by its strategic collaborations with leading biotech entities such as CRISPR Therapeutics AG, Moderna, Inc., and several others, aiming to harness cutting-edge science in the development of novel therapies.
Products and Services
- TRIKAFTA/KAFTRIO: Marketed for individuals with CF aged 2 years and older possessing at least one F508del mutation. This therapy represents a significant breakthrough in CF treatment, targeting the underlying genetic cause of the disease.
- SYMDEKO/SYMKEVI: Available for CF patients aged 6 years and older. This treatment option provides an alternative for those seeking effective management of their CF symptoms.
- ORKAMBI: Approved for CF patients 1 year of age or older. ORKAMBI addresses specific genetic mutations associated with CF, providing patients and their families hope for a better quality of life.
- KALYDECO: Designed for patients 1 year of age or older who have CF with the ivacaftor mutation. KALYDECO was the first medication to treat the underlying cause of CF in patients with specific mutations.
- VX-522: A CFTR mRNA therapeutic currently in Phase 1 clinical trials aimed at addressing the root cause of CF across a broader patient population.
- VX-548: A non-opioid medication for the treatment of acute and neuropathic pain, now in Phase 3 clinical trials, highlighting Vertex's dedication to addressing the widespread issue of pain management.
- Exa-cel: In Phase 2/3 clinical trials, this innovative treatment is being developed for sickle cell disease and transfusion-dependent beta thalassemia, promising hope for patients with these challenging conditions.
- Inaxaplin: Targeting APOL1-mediated focal segmental glomerulosclerosis and associated comorbidities like hypertension, this potential therapy is in a unified Phase 2/3 study.
- VX-880 and VX-264: Representing Vertex's foray into the treatment of Type 1 Diabetes, these candidates are in Phase 1/2 clinical trials, exploring new frontiers in diabetes care.
- VX-970: This candidate is in Phase 2 clinical trials for the treatment of cancer, reflecting Vertex's commitment to expanding its impact beyond CF.
- VX-803 and VX-984: Both in Phase 1 clinical trials, these treatments are part of Vertex's burgeoning cancer therapy portfolio, seeking to offer novel solutions for cancer patients.
