John R. Hanahan

John R. Hanahan Portfolio

Invests via Yukon Wealth Management Inc. | Managed by John R. Hanahan
Invests via Yukon Wealth Management Inc.
Managed by John R. Hanahan
Automatically Tracked
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Veteran healthcare and life-sciences executive focused on biotech strategy, corporate governance and commercialization planning for specialty pharma and diagnostics. John R. Hanahan served in senior operating and board roles across clinical development and market access, advising capital raises, licensing and M&A for growth-stage companies. Known for bridging R&D and commercial strategy, he is active with private-company boards and strategic investor networks, offering sector-specific operational oversight to institutional and venture investors.

Veteran healthcare and life-sciences executive focused on biotech strategy, corporate governance and commercialization planning for specialty pharma and diagnostics. John R. Hanahan served in senior operating and board roles across clinical development and market access, advising capital raises, licensing and M&A for growth-stage companies. Known for bridging R&D and commercial strategy, he is active with private-company boards and strategic investor networks, offering sector-specific operational oversight to institutional and venture investors.

Investment Philosophy & Strategy

Brings an operator-to-board investment philosophy emphasizing clinical-stage biotech and specialty pharma where commercial pathways can be accelerated through disciplined development and market-access planning. Prioritizes deals with clear regulatory milestones, differentiated clinical data and definable reimbursement strategies; allocates capital with milestone-weighted tranches and active governance rights. Favors hands-on portfolio involvement—de-risking R&D through strategic licensing, focused C-suite interventions and pragmatic go‑to‑market preparations. Time horizon is patient but outcome-driven, balancing early-stage asymmetric upside against downside protection via validation gates and liquidity-aware exit planning.

Brings an operator-to-board investment philosophy emphasizing clinical-stage biotech and specialty pharma where commercial pathways can be accelerated through disciplined development and market-access planning. Prioritizes deals with clear regulatory milestones, differentiated clinical data and definable reimbursement strategies; allocates capital with milestone-weighted tranches and active governance rights. Favors hands-on portfolio involvement—de-risking R&D through strategic licensing, focused C-suite interventions and pragmatic go‑to‑market preparations. Time horizon is patient but outcome-driven, balancing early-stage asymmetric upside against downside protection via validation gates and liquidity-aware exit planning.

Disclaimer: This Portfolio is derived from and computed based on publicly available data from SEC filings.
Gain and growth charts are calculated per selected timeframe:
34.27%
Gain +0.5%
Monthly
1.75%
Yearly
23.08%
Drawdown
11.77%
$364.14M
Equity
Holdings
$364.14M
Investment
$314.3M
$82.7M
Profit +$1.54M
Realized
$32.86M
Unrealized
$49.84M
Dividends
$6.31M

Goals

Avg. 98.5% completed goals
Yearly
Gain > 5%
2026
97%
Yearly
Gain < 20%
2026
100%
Today
Compared To Yesterday
Gain
0.5%
Profit
$1.54M
Win %
69%
This Week
Compared To Last Week
Gain
0.43%
Profit
$1.54M
Win %
69%
This Month
Compared to last month
Gain
3.17%
Profit
$11.2M
Win %
69%
This Year
Compared to last year
Gain
4.87%
Profit
$16.22M
Win %
69%
Intel Corporation logo
INTC Intel Corporation
+0.97%
+$1,732.5
iShares U.S. Energy ETF logo
IYE iShares U.S. Energy ETF
+0.91%
+$5,983.8
iShares Global Tech ETF logo
IXN iShares Global Tech ETF
+0.49%
+$9,173.5
IonQ, Inc. logo
IONQ IonQ, Inc.
+0.15%
+$811.93
Eli Lilly and Company logo
LLY Eli Lilly and Company
+0.04%
+$839.84
Union Pacific Corporation logo
UNP Union Pacific Corporation
+0.03%
+$1,104.21
VictoryShares Free Cash Flow ETF logo
VFLO VictoryShares Free Cash Flow ETF
+0.02%
+$311.07
Netflix, Inc. logo
NFLX Netflix, Inc.
+0.02%
+$307.08
Vanguard Information Technology ETF logo
VGT Vanguard Information Technology ETF
+0.02%
+$48
Broadcom Inc. logo
AVGO Broadcom Inc.
+0.01%
+$615.7
Valero Energy Corporation logo
VLO Valero Energy Corporation
+0.01%
+$151.57
Vanguard Total Bond Market Index Fund logo
BND Vanguard Total Bond Market Index Fund
+0.01%
+$326.01
ONEOK, Inc. logo
OKE ONEOK, Inc.
+0.01%
+$85.77
CSX Corporation logo
CSX CSX Corporation
+0.01%
+$86.41
Meta Platforms Inc Class A logo
META Meta Platforms Inc Class A
+0.01%
+$83.09
Cisco Systems, Inc. logo
CSCO Cisco Systems, Inc.
+0.01%
+$33.31
Lowe's Companies Inc. logo
LOW Lowe's Companies Inc.
+0.01%
+$43.26
Consumer Discretionary Select Sector SPDR Fund logo
XLY Consumer Discretionary Select Sector SPDR Fund
+0.01%
+$54.18
Merck & Co., Inc. logo
MRK Merck & Co., Inc.
+0.01%
+$27.09
State Street Technology Select Sector SPDR ETF logo
XLK State Street Technology Select Sector SPDR ETF
+0.01%
+$120.12
Amazon.com Inc logo
AMZN Amazon.com Inc
0%
+$325.24
Johnson & Johnson logo
JNJ Johnson & Johnson
0%
+$40.93
Microsoft Corp. logo
MSFT Microsoft Corp.
0%
+$443.22
Norfolk Southern Corporation logo
NSC Norfolk Southern Corporation
0%
+$78.62
Anavex Life Sciences Corp. logo
AVXL Anavex Life Sciences Corp.
0%
$0
Bank of America Corporation logo
BAC Bank of America Corporation
0%
$0
Enterprise Products Partners L.P. logo
EPD Enterprise Products Partners L.P.
0%
$0
Alphabet Inc logo
GOOG Alphabet Inc
0%
$0
Jabil Inc. logo
JBL Jabil Inc.
0%
$0
Southwest Airlines Co. logo
LUV Southwest Airlines Co.
0%
$0
Procter & Gamble Co logo
PG Procter & Gamble Co
0%
$0
StoneX Group Inc. logo
SNEX StoneX Group Inc.
0%
$0
iShares U.S. Thematic Rotation Active ETF logo
THRO iShares U.S. Thematic Rotation Active ETF
0%
$0
Taiwan Semiconductor Manufacturing Company Limited logo
TSMWF Taiwan Semiconductor Manufacturing Company Limited
0%
$0
iShares Core U.S. Aggregate Bond ETF logo
AGG iShares Core U.S. Aggregate Bond ETF
0%
$0
Avantis International Equity ETF logo
AVDE Avantis International Equity ETF
0%
$0
iShares Flexible Income Active ETF logo
BINC iShares Flexible Income Active ETF
0%
$0
Vanguard Short-Term Bond ETF logo
BSV Vanguard Short-Term Bond ETF
0%
$0
Dimensional U.S. Equity Market ETF logo
DFUS Dimensional U.S. Equity Market ETF
0%
$0
iShares U.S. Equity Factor Rotation Active ETF logo
DYNF iShares U.S. Equity Factor Rotation Active ETF
0%
$0
iShares Select Dividend ETF logo
DVY iShares Select Dividend ETF
0%
$0
iShares MSCI EAFE ETF logo
EFA iShares MSCI EAFE ETF
0%
$0
iShares MSCI EAFE Growth ETF logo
EFG iShares MSCI EAFE Growth ETF
0%
$0
iShares MSCI EAFE Value ETF logo
EFV iShares MSCI EAFE Value ETF
0%
$0
iShares J.P. Morgan USD Emerging Markets Bond ETF logo
EMB iShares J.P. Morgan USD Emerging Markets Bond ETF
0%
$0
iShares MSCI Emerging Markets ex China ETF logo
EMXC iShares MSCI Emerging Markets ex China ETF
0%
$0
iShares ESG Aware MSCI EM ETF logo
ESGE iShares ESG Aware MSCI EM ETF
0%
$0
iShares ESG Aware MSCI USA ETF logo
ESGU iShares ESG Aware MSCI USA ETF
0%
$0
iShares U.S. Treasury Bond ETF logo
GOVT iShares U.S. Treasury Bond ETF
0%
$0
iShares Currency Hedged MSCI EAFE ETF logo
HEFA iShares Currency Hedged MSCI EAFE ETF
0%
$0
PIMCO 0-5 Year High Yield Corporate Bond Index Exchange-Traded Fund logo
HYS PIMCO 0-5 Year High Yield Corporate Bond Index Exchange-Traded Fund
0%
$0
iShares International Aggregate Bond Fund logo
IAGG iShares International Aggregate Bond Fund
0%
$0
iShares Gold Trust logo
IAU iShares Gold Trust
0%
$0
iShares Core MSCI Emerging Markets ETF logo
IEMG iShares Core MSCI Emerging Markets ETF
0%
$0
iShares International Select Dividend ETF logo
IDV iShares International Select Dividend ETF
0%
$0
iShares Core S&P Small-Cap ETF logo
IJR iShares Core S&P Small-Cap ETF
0%
$0
iShares Core S&P Mid-Cap ETF logo
IJH iShares Core S&P Mid-Cap ETF
0%
$0
iShares U.S. Infrastructure logo
IFRA iShares U.S. Infrastructure
0%
$0
iShares Core S&P Total U.S. Stock Market ETF logo
ITOT iShares Core S&P Total U.S. Stock Market ETF
0%
$0
iShares Core S&P 500 ETF logo
IVV iShares Core S&P 500 ETF
0%
$0
ISHARES S&P 500 GROWTH ETF (3IS8) logo
IVW ISHARES S&P 500 GROWTH ETF (3IS8)
0%
$0
ISHARES S&P 500 VALUE ETF logo
IVE ISHARES S&P 500 VALUE ETF
0%
$0
iShares Core Universal USD Bond ETF logo
IUSB iShares Core Universal USD Bond ETF
0%
$0
iShares U.S. Real Estate ETF logo
IYR iShares U.S. Real Estate ETF
0%
$0
iShares U.S. Technology ETF logo
IYW iShares U.S. Technology ETF
0%
$0
JPMorgan Income ETF logo
JPIE JPMorgan Income ETF
0%
$0
iShares MBS ETF logo
MBB iShares MBS ETF
0%
$0
iShares MSCI USA Momentum Factor ETF logo
MTUM iShares MSCI USA Momentum Factor ETF
0%
$0
iShares S&P 100 ETF logo
OEF iShares S&P 100 ETF
0%
$0
PIMCO Multisector Bond Active ETF logo
PYLD PIMCO Multisector Bond Active ETF
0%
$0
iShares MSCI USA Quality Factor ETF logo
QUAL iShares MSCI USA Quality Factor ETF
0%
$0
Schwab U.S. Large-Cap ETF logo
SCHX Schwab U.S. Large-Cap ETF
0%
$0
Invesco S&P 500 Momentum ETF logo
SPMO Invesco S&P 500 Momentum ETF
0%
$0
SPDR Portfolio Emerging Markets ETF logo
SPEM SPDR Portfolio Emerging Markets ETF
0%
$0
SPDR Portfolio Developed World ex-US ETF logo
SPDW SPDR Portfolio Developed World ex-US ETF
0%
$0
SPDR Portfolio S&P 500 Value ETF logo
SPYV SPDR Portfolio S&P 500 Value ETF
0%
$0
NEOS S&P 500 High Income ETF logo
SPYI NEOS S&P 500 High Income ETF
0%
$0
SPDR Portfolio S&P 500 Growth ETF logo
SPYG SPDR Portfolio S&P 500 Growth ETF
0%
$0
US Treasury 3 Month Bill ETF logo
TBIL US Treasury 3 Month Bill ETF
0%
$0
iShares 10-20 Year Treasury Bond ETF logo
TLH iShares 10-20 Year Treasury Bond ETF
0%
$0
iShares Broad USD Investment Grade Corporate Bond ETF logo
USIG iShares Broad USD Investment Grade Corporate Bond ETF
0%
$0
iShares MSCI USA Min Vol Factor ETF logo
USMV iShares MSCI USA Min Vol Factor ETF
0%
$0
VANGUARD SMALL-CAP VALUE ETF logo
VBR VANGUARD SMALL-CAP VALUE ETF
0%
$0
Vanguard Small-Cap ETF logo
VB Vanguard Small-Cap ETF
0%
$0
iShares MSCI USA Value Factor ETF logo
VLUE iShares MSCI USA Value Factor ETF
0%
$0
Vanguard Mid-Cap ETF logo
VO Vanguard Mid-Cap ETF
0%
$0
Vanguard High Dividend Yield ETF logo
VYM Vanguard High Dividend Yield ETF
0%
$0
VANGUARD TOTAL STOCK MKT ETF logo
VTI VANGUARD TOTAL STOCK MKT ETF
0%
$0
Vanguard International High Dividend Yield Index Fund logo
VYMI Vanguard International High Dividend Yield Index Fund
0%
$0
JPMorgan Active Bond ETF logo
JBND JPMorgan Active Bond ETF
0%
$0
Vanguard Core-Plus Bond ETF logo
VPLS Vanguard Core-Plus Bond ETF
0%
$0
iShares Large Cap Core ACT ETF logo
BLCR iShares Large Cap Core ACT ETF
0%
$0
Cohen & Steers Infrastructure Fund, Inc. logo
UTF Cohen & Steers Infrastructure Fund, Inc.
0%
$0
Pimco Dynamic Income Fund logo
PDI Pimco Dynamic Income Fund
0%
$0
Global X Data Center & Digital Infrastructure ETF logo
DTCR Global X Data Center & Digital Infrastructure ETF
0%
$0
GE Vernova Inc. logo
GEV GE Vernova Inc.
0%
$0
iShares A.I. Innovation and Tech Active ETF logo
BAI iShares A.I. Innovation and Tech Active ETF
0%
$0
Palantir Technologies Inc. logo
PLTR Palantir Technologies Inc.
0%
$0
iShares U.S. Defense & Aerospace Index ETF logo
IDEF iShares U.S. Defense & Aerospace Index ETF
0%
$0
Akre Focus ETF logo
AKRE Akre Focus ETF
0%
$0
Berkshire Hathaway Inc. logo
BRK-B Berkshire Hathaway Inc.
0%
$0
Philip Morris International Inc. logo
PM Philip Morris International Inc.
-3.08%
-$15,203.3
McKesson Corporation logo
MCK McKesson Corporation
-1.04%
-$9,824.56
Tesla, Inc. logo
TSLA Tesla, Inc.
-0.87%
-$2,687.84
iShares 20+ Year Treasury Bond ETF logo
TLT iShares 20+ Year Treasury Bond ETF
-0.84%
-$15,493.97
Walmart Inc. logo
WMT Walmart Inc.
-0.81%
-$5,190.68
SPDR S&P 500 ETF Trust logo
SPY SPDR S&P 500 ETF Trust
-0.47%
-$3,181.92
Vanguard Dividend Appreciation ETF logo
VIG Vanguard Dividend Appreciation ETF
-0.41%
-$53,741.09
Apple Inc. logo
AAPL Apple Inc.
-0.11%
-$34,515.44
Rigetti Computing Inc logo
RGTI Rigetti Computing Inc
-0.08%
-$275.43
NVIDIA Corporation logo
NVDA NVIDIA Corporation
-0.07%
-$23,463.75
The PNC Financial Services Group, Inc. logo
PNC The PNC Financial Services Group, Inc.
-0.05%
-$336.33
D-Wave Quantum Inc. logo
QBTS D-Wave Quantum Inc.
-0.05%
-$108.52
The Goldman Sachs Group, Inc. logo
GS The Goldman Sachs Group, Inc.
-0.04%
-$1,034.2
Wells Fargo & Company logo
WFC Wells Fargo & Company
-0.04%
-$117
Visa Inc. Class A logo
V Visa Inc. Class A
-0.04%
-$384.93
Schwab U.S. Dividend Equity ETF logo
SCHD Schwab U.S. Dividend Equity ETF
-0.03%
-$4,923.25
Lockheed Martin Corporation logo
LMT Lockheed Martin Corporation
-0.03%
-$115.42
Costco Wholesale Corporation logo
COST Costco Wholesale Corporation
-0.02%
-$445.34
The Home Depot, Inc. logo
HD The Home Depot, Inc.
-0.02%
-$68.04
Intuitive Surgical, Inc. logo
ISRG Intuitive Surgical, Inc.
-0.01%
-$56.52
CrowdStrike Holdings, Inc. logo
CRWD CrowdStrike Holdings, Inc.
-0.01%
-$94.68
S&P Global Inc. logo
SPGI S&P Global Inc.
-0.01%
-$30.18
Colgate-Palmolive Company logo
CL Colgate-Palmolive Company
-0.01%
-$29.8
JPMorgan Chase & Co. logo
JPM JPMorgan Chase & Co.
-0.01%
-$361.65
Alphabet Inc logo
GOOGL Alphabet Inc
-0.01%
-$239.44
Digital Realty Trust, Inc. logo
DLR Digital Realty Trust, Inc.
-0.01%
-$11.2
Mastercard Incorporated logo
MA Mastercard Incorporated
-0.01%
-$235.68
AbbVie Inc. logo
ABBV AbbVie Inc.
0%
-$18.24
Advanced Micro Devices, Inc. logo
AMD Advanced Micro Devices, Inc.
0%
-$51.45
iShares Russell 2000 ETF logo
IWM iShares Russell 2000 ETF
0%
-$20.82
Invesco QQQ Trust, Series 1 logo
QQQ Invesco QQQ Trust, Series 1
0%
-$259.95
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Dividends

Dividend Analysis

Yearly
$
Trades
594
Longs Won
404/594 68%
Profit Factor
19.95
Profitability
Shorts Won
0/0 0%
Standard Deviation
$622,002.86
Average Win
$215,511.67
Best Trade
(Dec 31) $9.96M
Sharpe Ratio
-9.68
Average Loss
-$22,974.54
Worst Trade
(Sep 01) -$324,309.31
Z-Score
5.1 (100%)
Commissions
$0
Avg. Trade Length
7m 4w 1d
Expectancy
$139,228.2
Loss Size 100% 90% 80% 70% 60% 50% 40% 30% 20% 10%
Probability of Loss <0.01% <0.01% <0.01% <0.01% <0.01% <0.01% <0.01% <0.01% <0.01% <0.01%
Consecutive Losing Trades 15,873 14,286 12,698 11,111 9,524 7,937 6,349 4,762 3,175 1,587
Hover over the desired column for a detailed explanation.

Returns

Overall, Monthly
Symbol Quantity Cost Value Comm. Profit (&#36;) Gain (%) Change
Apple Inc. logo
AAPL Apple Inc.
101,516 $29.05M $31.02M - $1.98M 6.8%
-0.111%
AbbVie Inc. logo
ABBV AbbVie Inc.
1,822 $389,910.06 $454,497.9 - $64,587.84 16.56%
-0.004%
iShares Core U.S. Aggregate Bond ETF logo
AGG iShares Core U.S. Aggregate Bond ETF
10,395 $1.03M $1.01M - -$15,352.4 -1.49%
0.0
Akre Focus ETF logo
AKRE Akre Focus ETF
15,456 $822,105 $921,177.6 - $99,072.6 12.05%
0.0
Advanced Micro Devices, Inc. logo
AMD Advanced Micro Devices, Inc.
2,571 $1.49M $1.32M - -$171,074.73 -11.45%
-0.004%
Amazon.com Inc logo
AMZN Amazon.com Inc
32,492 $7.34M $8.53M - $1.2M 16.29%
+0.004%
Avantis International Equity ETF logo
AVDE Avantis International Equity ETF
3,021 $223,584 $284,850.09 - $61,266.09 27.4%
0.0
Broadcom Inc. logo
AVGO Broadcom Inc.
10,262 $3.63M $4.03M - $401,839.26 11.06%
+0.015%
Anavex Life Sciences Corp. logo
AVXL Anavex Life Sciences Corp.
13,992 $103,102.46 $45,054.24 - -$58,048.22 -56.3%
0.0
Bank of America Corporation logo
BAC Bank of America Corporation
5,326 $303,495 $343,473.74 - $39,978.74 13.17%
0.0
iShares A.I. Innovation and Tech Active ETF logo
BAI iShares A.I. Innovation and Tech Active ETF
12,254 $446,003.15 $573,119.58 - $127,116.43 28.5%
0.0
iShares Flexible Income Active ETF logo
BINC iShares Flexible Income Active ETF
14,547 $762,506 $757,316.83 - -$5,189.17 -0.68%
0.0
iShares Large Cap Core ACT ETF logo
BLCR iShares Large Cap Core ACT ETF
5,083 $256,031 $257,809.76 - $1,778.76 0.69%
0.0
Vanguard Total Bond Market Index Fund logo
BND Vanguard Total Bond Market Index Fund
32,601 $2.4M $2.36M - -$44,278.66 -1.84%
+0.014%
Berkshire Hathaway Inc. logo
BRK-B Berkshire Hathaway Inc.
2,364 $1.21M $1.19M - -$17,744.26 -1.47%
0.0
Vanguard Short-Term Bond ETF logo
BSV Vanguard Short-Term Bond ETF
21,378 $1.68M $1.66M - -$22,779.38 -1.35%
0.0
Colgate-Palmolive Company logo
CL Colgate-Palmolive Company
2,980 $273,256 $273,981.2 - $725.2 0.27%
-0.011%
Costco Wholesale Corporation logo
COST Costco Wholesale Corporation
2,545 $2.38M $2.45M - $64,643.1 2.72%
-0.018%
CrowdStrike Holdings, Inc. logo
CRWD CrowdStrike Holdings, Inc.
3,156 $602,117.46 $684,599.52 - $82,482.06 13.7%
-0.014%
Cisco Systems, Inc. logo
CSCO Cisco Systems, Inc.
3,331 $249,675.66 $372,039.39 - $122,363.73 49.01%
+0.009%
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Option values are updated at end of day.
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Option values are updated at end of day.
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FAQ
Which stocks have generated the highest profits for John R. Hanahan?
The largest contributions to the portfolio's profits come from the following stocks: NVIDIA Corporation - $9.97M, Apple Inc - $5.07M, Alphabet Inc - $2.16M, Microsoft Corp - $1.75M, and Alphabet Inc - $1.47M. These positions have been the main drivers of growth and have significantly impacted the investor's overall performance.
Which stocks have generated the largest losses for this investor?
The largest losses in the portfolio are associated with the following stocks: ONEOK, Inc - $188,215.81, Rigetti Computing Inc - $131,728.7, iShares Ethereum Trust - $107,153.57, IonQ, Inc - $102,641.36, and Eli Lilly and Company - $96,714.37. These positions have had the most negative impact on overall performance and highlight the weaker areas of the portfolio.
What dividends does John R. Hanahan's portfolio generate?
The portfolio generates substantial dividend income, with a total of $6.31M earned over time. The largest contributors to dividend income include iShares Select Dividend ETF - $1.01M, Schwab U.S. Dividend Equity ETF - $557,790.48, iShares Core Universal USD Bond ETF - $429,142.53, iShares Core S&P 500 ETF - $389,576.69, and iShares MSCI EAFE Value ETF - $319,883.39. This indicates that dividends play a meaningful role in the investor's overall strategy.
How stable are John R. Hanahan's monthly returns?
John R. Hanahan's monthly returns look fairly stable overall, although some fluctuations are still visible. The performance pattern suggests a strategy that remains reasonably controlled from month to month, even if it is not completely smooth. This may appeal to users looking for a balance between steadier results and meaningful upside potential.
Can John R. Hanahan's strategy be considered aggressive or moderate?
John R. Hanahan's strategy leans toward a moderately conservative profile. While there is still some exposure to market fluctuations, the overall structure and risk levels suggest a focus on maintaining stability rather than pursuing aggressive growth.
Should beginners follow John R. Hanahan's strategy?
John R. Hanahan's strategy may be suitable for beginners, but with some caution. While the overall approach is not overly complex, it still involves a certain level of risk and variability. Beginners should be prepared for occasional fluctuations and ensure they understand the strategy before trying to follow it.
Account USV