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BioInvent Announces Promising Initial Efficacy Data from Triple Combination Arm of BI-1206, Rituximab and Calquence for the Treatment of non-Hodgkin's Lymphoma
LUND, SWEDEN / ACCESSWIRE / January 8, 2025 / BioInvent International (STO:BINV) The first two patients enrolled in the Phase 2a study triplet arm combining BI-1206 with rituximab and Calquence® responded to treatment One complete response (CR) and one partial response (PR) The treatment has been well-tolerated with no safety or tolerability concerns Study now expanding to additional clinical investigational sites and patient enrollment on track with further Phase 2a results expected by mid-2025 BioInvent International AB ("BioInvent") (Nasdaq Stockholm: BINV), a biotech company focused on the discovery and development of novel and first-in-class immune-modulatory antibodies for cancer immunotherapy, today announces promising initial clinical response data from the two enrolled patients in the triple combination arm of the Phase 1/2a study of its anti-FcyRIIB antibody, BI-1206, combined with rituximab and AstraZeneca's Bruton's tyrosine kinase (BTK) inhibitor Calquence® (acalabrutinib), in non-Hodgkin's lymphoma (NHL). The preliminary data demonstrates that the combination treatment is well tolerated with the two enrolled patients already showing clinical responses.
BINV: Brandes, The Iconic Value Stock Investor, In ETF Form
Brandes International might as well use the tag line "we buy ugly stocks." They are a deep contrarian value manager. The firm's success dates back to last century, and it investment success over the decades made it founder a billionaire philanthropist. Top value investors like Charles Brandes and John Templeton focused on buying portfolios of non-US stocks with low turnover for long-term compounding returns.
BioInvent to Present Pipeline Progress on BI-1910 and BT-001 at ESMO
LUND, SWEDEN / ACCESSWIRE / July 22, 2024 / BioInvent International (STO:BINV) Two posters to be presented on early clinical projects from BioInvent's robust pipeline totaling six clinical programs: Progress with the Phase 1 trial studying BI-1910 as single agent in solid tumors Initial clinical data from the BT-001 Phase 1 study evaluating the candidate both as single agent and in combination with KEYTRUDA® (pembrolizumab) in patients with solid tumors European Society for Medical Oncology (ESMO 2024) to be held September 13-17, 2024 BioInvent International AB ("BioInvent") (Nasdaq Stockholm:BINV), a biotech company focused on the discovery and development of novel and first-in-class immune-modulatory antibodies for cancer immunotherapy, announced abstracts for BI-1910 and BT-001 have been selected for presentation at ESMO 2024, being held in Barcelona, Spain from September 13th to 17th, 2024. BI-1910 is a monoclonal antibody, a TNFR2 agonist, currently enrolling patients in the monotherapy part of the ongoing Phase 1/2a study in patients with advanced solid tumors.
Brandes International Equity Fund Investors
| Name | Quantity | Cost | Value | Profit ($) | Gain (%) |
|---|---|---|---|---|---|
| JBS Joseph Blane Shea Horizon Family Wealth Inc. | 99,082 | $3.84M | $4.31M | $467,073.58 | 12.15% |
| AJP Aaron J. Plautz Principia Wealth Advisory LLC | 303 | $11,156.38 | $13,216.86 | $2,060.48 | 18.47% |
| TS Thomas Stadum Fjell Capital LLC | 82,298 | $2.8M | $3.54M | $740,423.94 | 26.48% |
| BWL Balance Wealth LLC Balance Wealth LLC | 181,875 | $6.38M | $7.94M | $1.56M | 24.43% |
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Brandes International Equity Fund Profile
| BATS Exchange | US Country |
Overview
The fund is a distinct active investment vehicle that primarily sets its sights on equity securities of foreign corporations. By focusing on companies with substantial market presence, signified by market capitalizations exceeding $5 billion during acquisition, the fund positions itself as a gateway to potentially lucrative investments in the global market. Its choice to actively manage its portfolio differentiates it from passive investment strategies, aiming to optimize investment returns by dynamically adjusting to market conditions and opportunities abroad.
Products and Services
The ETF's investment strategy encompasses a broad spectrum of products and services designed to cater to the discerning investor seeking exposure to foreign equity markets:
- Equity Securities of Foreign Companies: The centerpiece of the fund's investment focus, this involves buying shares in companies located outside the investor's home country. It allows investors to diversify their portfolio by tapping into the growth potential of foreign markets, potentially hedging against domestic market volatility.
- Actively Managed Portfolio: Unlike passive index funds, this ETF employs a hands-on approach, with fund managers actively selecting stocks and timing purchases to capitalize on market trends and investment opportunities. This aims to outperform benchmark indices through strategic decision-making.
