Milestone Pharmaceuticals Inc. (MIST)
NASDAQ (NGS) NASDAQ (NGS) Primary Summary
Milestone Pharmaceuticals: Here Comes The Revenue Ramp
Milestone Pharmaceuticals Inc. remains a Strong Buy, despite recent volatility and a 37% stock decline since FDA approval of Cardamyst. Cardamyst's rapid-acting efficacy, expanding insurance coverage, and unique market position underpin a compelling medium-term ramp in prescriptions and revenue. International expansion and a Phase 3 trial for AFib-RVR could significantly enlarge MIST's addressable market and long-term growth prospects.
Milestone Pharmaceuticals Q1 Earnings Call Highlights
Milestone Pharmaceuticals NASDAQ: MIST said its first quarter of 2026 marked the beginning of commercial sales for CARDEMYST, its newly approved treatment for acute episodes of paroxysmal supraventricular tachycardia, or PSVT, while the company also moved ahead with a Phase 3 program in atrial fibrillation with rapid ventricular rate.
Milestone Pharmaceuticals Inc. (MIST) Q1 2026 Earnings Call Transcript
Milestone Pharmaceuticals Inc. (MIST) Q1 2026 Earnings Call Transcript
Milestone Pharmaceuticals Inc. Investors
| Name | Quantity | Cost | Value | Profit ($) | Gain (%) |
|---|---|---|---|---|---|
 Point72 Asset Management LP Point72 Asset Management LP | 1.09M | $1.69M | $1.37M | -$324,356.86 | -19.17% |
 Didric Cederholm Lion Point Capital LP | 820,000 | $1.46M | $1.03M | -$426,129.78 | -29.28% |
 Bobby Adusumilli SJS Investment Consulting Inc. | 15,000 | $30,300 | $18,975 | -$11,325 | -37.38% |
 Christian Keedy Guardian Wealth Advisors LLC / Nc | 280,250 | $547,749.5 | $354,516.25 | -$193,233.25 | -35.28% |
 Michael Abram INTEGRAL INVESTMENT ADVISORS Inc. | 10,000 | $20,200 | $12,700 | -$7,500 | -37.13% |
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Milestone Pharmaceuticals Inc. Profile
| Biotechnology Industry | Healthcare Sector | Joseph G. Oliveto CEO | NASDAQ (NGS) Exchange | 59935V107 CUSIP |
| CA Country | 38 Employees | - Last Dividend | - Last Split | 9 May 2019 IPO Date |
Overview
Milestone Pharmaceuticals Inc. is a biopharmaceutical company that concentrates its efforts on the innovation and commercialization of cardiovascular medicines. Established in 2003 and based in Montréal, Canada, the company is engaged in addressing unmet medical needs in cardiovascular diseases with a strong focus on developing novel therapeutic solutions. Milestone Pharmaceuticals has forged partnerships through its license and collaboration agreement with Ji Xing Pharmaceuticals for the development and commercialization of its lead product candidate etripamil across various applications, alongside collaborative efforts with the Montreal Heart Institute, the WCN network, and other leading research centers.
Products and Services
Milestone Pharmaceuticals Inc. is primarily focused on the development of its flagship product candidate, etripamil, alongside its engagement in various collaborative research efforts:
- Etripamil: A potent novel calcium channel blocker currently undergoing extensive clinical trials for the treatment of cardiovascular conditions. The applications of etripamil include:
- Phase III clinical trial for the treatment of paroxysmal supraventricular tachycardia (PSVT) in the United States and Canada, focusing on addressing this acute and disruptive heart condition effectively.
- Phase II clinical trial for the treatment of atrial fibrillation and rapid ventricular rate (AF and RVR), representing a concerted effort to expand its application in managing other critical cardiac arrhythmias.
- Collaborations: Milestone Pharmaceuticals has entered into various strategic partnerships to bolster the development and commercialization potential for etripamil across different therapeutic and prophylactic uses:
- License and collaboration agreement with Ji Xing Pharmaceuticals, aimed at exploring and advancing etripamil's prophylactic and therapeutic applications for human use.
- Research partnerships with the Montreal Heart Institute, the WCN network, and additional research centers, facilitating a broad base of clinical support and validation for etripamil's efficacy and safety in treating cardiovascular diseases.
