The consensus price target hints at a 294.7% upside potential for Wave Life Sciences (WVE). While empirical research shows that this sought-after metric is hardly effective, an upward trend in earnings estimate revisions could mean that the stock will witness an upside in the near term.
Wave Life Sciences (WVE) might move higher on growing optimism about its earnings prospects, which is reflected by its upgrade to a Zacks Rank #2 (Buy).
Wave Life Sciences Ltd. retains a Strong Buy rating, driven by near-term Accelerated Approval catalysts for WVE-N531 and WVE-006. The company is on track to file an NDA for WVE-N531 in DMD exon 53 skipping in 2026, targeting approval based on dystrophin production and functional testing. Recent phase 1b/2a data for WVE-006 in AATD showed up to 70.5% Z-AAT reduction with multi-dosing, with key FDA feedback and 600 mg multi-dose data expected in mid/late 2026.
| Name | Quantity | Cost | Value | Profit ($) | Gain (%) |
|---|---|---|---|---|---|
| CE Curtis Ellergodt Rothschild Investment LLC | 292 | $2,962.4 | $1,759.53 | -$1,202.87 | -40.6% |
| BG Bart Gancher Intech Investment Management LLC | 39,437 | $316,176.66 | $236,227.63 | -$79,949.03 | -25.29% |
John H. Burbank III Passport Capital LLC | 822,638 | $6.29M | $4.93M | -$1.36M | -21.67% |
Joseph Castro Nuveen LLC | 657,720 | $5.47M | $3.9M | -$1.57M | -28.73% |
Bobby Adusumilli SJS Investment Consulting Inc. | 53 | $550 | $315.41 | -$234.59 | -42.65% |
| Biotechnology Industry | Healthcare Sector | Paul Bolno CEO | NASDAQ (NMS) Exchange | 94214N102 CUSIP |
| SG Country | 317 Employees | - Last Dividend | - Last Split | 11 Nov 2015 IPO Date |
Wave Life Sciences Ltd. is at the forefront of biotechnology, focusing on the design, development, and commercialization of revolutionary ribonucleic acid (RNA) medicines. Leveraging their proprietary PRISM discovery and drug development platform, the company is dedicated to transforming the treatment landscape for both rare and common disorders. This platform integrates versatile modalities, innovative chemistry, and advanced insights into human genetics to craft scientific breakthroughs. Established in 2012 and headquartered in Singapore, Wave Life Sciences is a clinical-stage company that embarks on strategic collaborations with industry giants like GlaxoSmithKline, Takeda Pharmaceutical Company Limited, and Asuragen, Inc., to enhance the reach and efficacy of its RNA therapeutics.
An RNA editing oligonucleotide under development for treating alpha-1 antitrypsin deficiency. This innovative approach aims to directly modify the RNA responsible for the disorder, offering a potential new approach to treatment.
A specialized small interfering RNA (siRNA) therapeutic aimed at addressing obesity and other metabolic disorders. This candidate demonstrates the company's commitment to tackling prevalent, complex health issues through targeted RNA interference mechanisms.
An exon skipping oligonucleotide designed to treat Duchenne muscular dystrophy. This product reveals the potential of RNA-based therapies to correct genetic mutations and restore normal function, particularly in diseases caused by specific genetic errors.
An antisense silencing oligonucleotide targeting Huntington's disease (HD). By inhibiting the production of the harmful proteins that cause HD, WVE-003 represents a cutting-edge approach to treating this devastating neurodegenerative disorder.