Immunome Inc. (IMNM)
NASDAQ (CM) NASDAQ (CM) Primary Summary
argenx VYVGART Hits Phase III Goal in Autoimmune Myositis, Eyes IMNM Filing
argenx NASDAQ: ARGX reported positive top-line results from its Phase III ALKIVIA trial of VYVGART Hytrulo in autoimmune myositis, meeting its primary endpoint in a combined population of patients with immune-mediated necrotizing myopathy, or IMNM, and dermatomyositis, or DM.
Immunome: Maintaining My 'Strong Buy' Rating With 2 Catalysts On The Horizon
I am maintaining my "Strong Buy" rating on Immunome (IMNM). This decision is driven by FDA acceptance of varegacestat's NDA and a PDUFA date set for April 2027. The company's pipeline is diversified, with IM-1021 [ROR1 ADC] in phase 1 for B-cell lymphoma/solid tumors and initial data expected in 2026. The proprietary HC74 TOP1i payload in IM-1021 aims for best-in-class efficacy, targeting resistance and bystander effects beyond Merck's ROR1 ADC.
Immunome Stock Up 32% in a Month: Here's What You Should Know
IMNM jumps 32% in a month. This comes as the FDA accepts varegacestat's NDA for desmoid tumors, with an approval decision expected by April 2027.
Immunome Inc. Investors
| Name | Quantity | Cost | Value | Profit ($) | Gain (%) |
|---|---|---|---|---|---|
 Curtis Ellergodt Rothschild Investment LLC | 200 | $1,844.73 | $4,994 | $3,149.27 | 170.72% |
| NA Nizar Araji National Bank Of Canada /FI/ | 138 | $2,964.24 | $3,454.14 | $489.9 | 16.53% |
| BG Bart Gancher Intech Investment Management LLC | 30,460 | $347,304.22 | $762,413.83 | $415,109.61 | 119.52% |
 John H. Burbank III Passport Capital LLC | 55,306 | $1.07M | $1.5M | $429,174.56 | 40.14% |
 Joseph Castro Nuveen LLC | 288,922 | $4.36M | $7.21M | $2.85M | 65.37% |
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Immunome Inc. Profile
| Biotechnology Industry | Healthcare Sector | Clay Siegall CEO | NASDAQ (CM) Exchange | 45257U108 CUSIP |
| US Country | 247 Employees | - Last Dividend | - Last Split | 2 Oct 2020 IPO Date |
Overview
Immunome, Inc. is a pioneering biotechnology company founded in 2006, with a focus on the development of innovative cancer therapies. Based in Bothell, Washington, the company leverages advanced research and technology to create treatments that target specific cancer types, aiming to improve patient outcomes and quality of life. Immunome, Inc. stands at the forefront of cancer research, pushing the boundaries of scientific discovery to develop therapies that can significantly impact the lives of patients battling cancer.
Products and Services
- AL102
An investigational gamma secretase inhibitor, AL102 is currently undergoing a Phase 3 clinical trial for its efficacy in treating desmoid tumors. Desmoid tumors, although benign, can be aggressive and invasive, making AL102 a critical component of Immunome, Inc.'s portfolio as it represents a significant step towards offering new solutions for patients with few treatment options.
- IM-1021
This preclinical asset is an innovative approach to cancer treatment, focusing on receptor tyrosine kinase-like orphan receptor 1 (ROR1) and antibody-drug conjugates. ROR1 is a promising target for cancer therapy because of its selective expression in cancer cells, particularly in leukemia, breast cancer, and lung cancer. By developing IM-1021, Immunome, Inc. aims to exploit this vulnerability in cancer cells, offering a tailored treatment that could minimize harm to healthy cells.
- IM-3050
As another preclinical asset, IM-3050 targets fibroblast activation protein (FAP) with radioligand therapy. FAP is frequently overexpressed in cancer-associated fibroblasts, which are found in the tumor microenvironment. By targeting these fibroblasts, IM-3050 has the potential to disrupt the tumor's growth and support system, providing a novel angle for cancer therapy that complements existing treatment modalities.
- IM-4320
This ambitious preclinical candidate is an anti-IL-38 immunotherapy. IL-38 has been identified as a potential therapeutic target due to its role in modulating the immune system's response to cancer cells. By developing an immunotherapy that targets IL-38, Immunome, Inc. is exploring a new frontier in cancer treatment that focuses on enhancing the body's natural ability to fight cancer, thereby offering a groundbreaking approach to treatment that could reshape the landscape of cancer therapy.
