Tyra Biosciences, Inc. (TYRA) Presents at Bank of America Global Healthcare Conference 2026 Transcript
The average of price targets set by Wall Street analysts indicates a potential upside of 178.8% in Tyra Biosciences (TYRA). While the effectiveness of this highly sought-after metric is questionable, the positive trend in earnings estimate revisions might translate into an upside in the stock.
On Thursday, Tyra Biosciences, Inc. TYRA released clinical proof-of-concept data for TYRA-300 in patients with metastatic urothelial (mUC) cancer from its ongoing SURF301 Phase 1/2 study.
| Name | Quantity | Cost | Value | Profit ($) | Gain (%) |
|---|---|---|---|---|---|
| CE Curtis Ellergodt Rothschild Investment LLC | 55 | $595.85 | $1,754.4 | $1,158.55 | 194.44% |
Farallon Capital Farallon Capital Management LLC | 3.58M | $97.49M | $114.47M | $16.98M | 17.42% |
| BG Bart Gancher Intech Investment Management LLC | 6,345 | $60,715.44 | $202,024.8 | $141,309.36 | 232.74% |
John H. Burbank III Passport Capital LLC | 10,607 | $146,907 | $337,726.88 | $190,819.88 | 129.89% |
Point72 Asset Management LP Point72 Asset Management LP | 38,850 | $1.02M | $1.24M | $221,254.61 | 21.66% |
| Name | Quantity | Cost | Value | Profit ($) | Gain (%) |
|---|---|---|---|---|---|
| GM Geoff Meacham B of A Securities | 1,401.35 | $18,371.29 | $45,375.56 | $27,004.27 | 146.99% |
| Biotechnology Industry | Healthcare Sector | Todd Harris CEO | NASDAQ (NGS) Exchange | 90240B106 CUSIP |
| US Country | 87 Employees | - Last Dividend | - Last Split | 15 Sep 2021 IPO Date |
Tyra Biosciences, Inc. is a preclinical-stage biopharmaceutical company focus on creating innovative therapies aimed at overcoming tumor resistance, thereby enhancing treatment outcomes for patients with cancer. Established in 2018, Tyra Biosciences is headquartered in Carlsbad, California. The company's research and development efforts are particularly centered on addressing the challenges posed by specific genetic mutations and resistance mechanisms in cancer cells, with an emphasis on utilizing precision medicine techniques to design and develop targeted therapies.
A leading product candidate from Tyra Biosciences, TYRA-300 is a selective inhibitor focusing on fibroblast growth factor receptor 3 (FGFR3), designed for the treatment of muscle invasive bladder cancer. This compound represents the company's strategic pursuit of targeted therapy options that can directly inhibit the growth and spread of cancer cells through specific genetic pathways.
Under development to address intrahepatic cholangiocarcinoma, this program targets the fibroblast growth factor receptor 2 (FGFR2). By focusing on genetic abnormalities specific to this type of cancer, Tyra Biosciences aims to offer a targeted therapeutic option that can potentially improve treatment precision and efficacy.
Expanding its portfolio beyond oncology, Tyra Biosciences is also working on a program targeting FGFR3-related achondroplasia, a genetic condition affecting bone growth. This signifies the company's commitment to leveraging its expertise in FGFR pathways for broader therapeutic applications.
This program focuses on the development of treatments targeting the REarranged during Transfection (RET) kinase. By inhibiting the activity of this protein, Tyra Biosciences aims to offer therapeutic options for cancers that are driven by alterations in the RET gene, showcasing the company’s dedication to addressing a wide range of oncogenic drivers.
Targeting cancers related to abnormalities in the fibroblast growth factor receptor 4 (FGFR4), this program represents another dimension of Tyra Biosciences' approach to combat cancer through precision medicine. The focus here is on harnessing the potential of targeted therapy to inhibit cancer progression associated with FGFR4 mutations.
The SNAP platform is Tyra Biosciences' proprietary technology designed to accelerate the structural design of targeted therapies. Through iterative molecular "SNAPshots", this platform enables the rapid and efficient development of drug compounds, thus facilitating the company's agile response to emerging therapeutic needs in oncology and beyond.